Temperature profiling of ex-vivo organs during ferromagnetic nanoparticles-enhanced radiofrequency ablation by fiber Bragg grating arrays

Madina Jelbuldina, Sanzhar Korganbayev, Alina V. Korobeinyk, Vassilis J. Inglezakis, Daniele Tosi

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

1 Citation (Scopus)
1 Downloads (Pure)

Abstract

In this paper, we present real-time profiles of temperature during a ferromagnetic nanoparticles (NPs)enhanced radiofrequency ablation (RFA). A minimally invasive RFA setup has been prepared and applied ex vivo on a liver phantom; NPs (with concentration of 5 mg/mL) have been synthetized and injected within the tissue prior to perform the ablation, in order to facilitate the heat distribution to the peripheral sides of the ablated tissue. Temperature detection has been realized in situ with a network of 15 fiber Bragg grating (FBG) sensors in order to highlight the impact of the NPs on the RFA mechanism. Obtained temperature profiles and thermal maps confirm that nanoparticles injection ensures better heat penetration than in case of pristine RFA procedure. The results show that adding NPs solution leads to extending the successfully ablated area achieving a double-sized lesion.

Original languageEnglish
Title of host publication40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
Place of PublicationPiscataway, N.J.
Number of pages4
ISBN (Electronic)9781538636466
DOIs
Publication statusPublished - 26 Oct 2018
Event40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 - Honolulu, United States
Duration: 18 Jul 201821 Jul 2018

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2018-July
ISSN (Print)1557-170X

Conference

Conference40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
CountryUnited States
CityHonolulu
Period18/07/1821/07/18

Keywords

  • temperature sensors
  • fibre optic sensors
  • biological tissues
  • fiber Bragg grating sensors

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