TY - GEN
T1 - Temperature profiling of ex-vivo organs during ferromagnetic nanoparticles-enhanced radiofrequency ablation by fiber Bragg grating arrays
AU - Jelbuldina, Madina
AU - Korganbayev, Sanzhar
AU - Korobeinyk, Alina V.
AU - Inglezakis, Vassilis J.
AU - Tosi, Daniele
N1 - © 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting /republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
PY - 2018/10/26
Y1 - 2018/10/26
N2 - In this paper, we present real-time profiles of temperature during a ferromagnetic nanoparticles (NPs)enhanced radiofrequency ablation (RFA). A minimally invasive RFA setup has been prepared and applied ex vivo on a liver phantom; NPs (with concentration of 5 mg/mL) have been synthetized and injected within the tissue prior to perform the ablation, in order to facilitate the heat distribution to the peripheral sides of the ablated tissue. Temperature detection has been realized in situ with a network of 15 fiber Bragg grating (FBG) sensors in order to highlight the impact of the NPs on the RFA mechanism. Obtained temperature profiles and thermal maps confirm that nanoparticles injection ensures better heat penetration than in case of pristine RFA procedure. The results show that adding NPs solution leads to extending the successfully ablated area achieving a double-sized lesion.
AB - In this paper, we present real-time profiles of temperature during a ferromagnetic nanoparticles (NPs)enhanced radiofrequency ablation (RFA). A minimally invasive RFA setup has been prepared and applied ex vivo on a liver phantom; NPs (with concentration of 5 mg/mL) have been synthetized and injected within the tissue prior to perform the ablation, in order to facilitate the heat distribution to the peripheral sides of the ablated tissue. Temperature detection has been realized in situ with a network of 15 fiber Bragg grating (FBG) sensors in order to highlight the impact of the NPs on the RFA mechanism. Obtained temperature profiles and thermal maps confirm that nanoparticles injection ensures better heat penetration than in case of pristine RFA procedure. The results show that adding NPs solution leads to extending the successfully ablated area achieving a double-sized lesion.
KW - temperature sensors
KW - fibre optic sensors
KW - biological tissues
KW - fiber Bragg grating sensors
UR - http://www.scopus.com/inward/record.url?scp=85056669768&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2018.8513227
DO - 10.1109/EMBC.2018.8513227
M3 - Conference contribution book
C2 - 30440308
AN - SCOPUS:85056669768
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
BT - 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
CY - Piscataway, N.J.
T2 - 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
Y2 - 18 July 2018 through 21 July 2018
ER -