A range of functionalised dienes and trienes have been prepared by one-pot processes in which alcohol oxidation is accompanied by in situ Wittig homologation using Trippett's reagent [(triphenylphosphoranylidene)acetaldehyde] followed by addition of a second stabilised phosphorane. This procedure has been applied to alpha-hydroxy carbonyl compounds and activated benzylic alcohols.
- oxidation-wittig-wittig sequences
- functionalised dienoates
Lang, S., & Taylor, R. (2006). Tandem oxidation-Wittig-Wittig sequences for the preparation of functionalised dienoates. Tetrahedron Letters, 47(31), 5489-5492. https://doi.org/doi: 10.1016/j.tetlet.2006.05.162