Systems biology guided by XCMS Online metabolomics

Tao Huan, Erica M Forsberg, Duane Rinehart, Caroline H Johnson, Julijana Ivanisevic, H Paul Benton, Mingliang Fang, Aries Aisporna, Brian Hilmers, Farris L Poole, Michael P Thorgersen, Michael W W Adams, Gregory Krantz, Matthew W Fields, Paul D Robbins, Laura J Neidernhofer, Trey Ideker, Erica L Majumder, Judy D Wall, Nicholas J W RattrayRoy Goodacre, Luke L Lairson, Gary Siuzdak

Research output: Contribution to journalLetterpeer-review

122 Citations (Scopus)
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Abstract

An aim of systems biology is to understand complex interactions between genes, proteins and metabolites by integrating and modeling multiple data sources. We report an 'integrated-omics' approach within XCMS Online1 that automatically superimposes raw metabolomic data onto metabolic pathways and integrates it with transcriptomic and proteomic data (http://XCMSOnline.scripps.edu/).
Original languageEnglish
Pages (from-to)461-462
Number of pages2
JournalNature Methods
Volume14
Issue number5
DOIs
Publication statusPublished - 27 Apr 2017

Keywords

  • metabolomic data
  • metabolic pathways
  • proteomic data

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