Synthetic approaches to parabens molecularly imprinted polymers and their applications to the solid-phase extraction of river water samples

A. Beltran, R. M. Marce, P. A. G. Cormack, F. Borrull

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Synthesis, characterization, and use of 2 distinct molecularly-imprinted polymers (MIP) prepd. using p-hydroxybenzoic acid (paraben) esters as templates are reported.: one MIP was synthesized by pptn. polymn. using a semi-covalent molecularly imprinting strategy with Me paraben as the template/target (MIP 1); the second MIP was prepd. in monolithic form through a conventional non-covalent mol. imprinting strategy, with Bu paraben as the template (MIP 2). One MIP was synthesized by pptn. polymn. using a semi-covalent molecularly imprinting strategy with Me paraben as the template/target (MIP 1); the second MIP was synthesized in monolithic form using a conventional, non-covalent mol. imprinting strategy with Bu paraben as the template (MIP 2). MIP 1 recognized Me paraben, showed cross-selectivity for other studied paraben analytes, and a higher affinity toward these compds. than a non-imprinted control polymer. Similarly, MIP 2 demonstrated a higher affinity toward paraben analytes than a non-imprinted control polymer. For anal. of environmental water, a solid phase extn. (SPE) protocol was developed using MIP 2 as sorbent; results were compared to SPE using a com. sorbent (Oasis HLB). With MIP 2 as sorbent and Bu paraben as target, when percolating 500 mL of river water spiked at 1 μg/L through the SPE cartridge, and using 1 mL of isopropanol as cleaning solvent, a higher Bu 4-hydroxybenzoate (Bu paraben) recovery and a cleaner chromatogram where achieved when using the MIP vs. the com. sorbent.
LanguageUndefined/Unknown
Pages72-78
Number of pages7
JournalAnalytica Chimica Acta
Volume677
Issue number1
DOIs
Publication statusPublished - 2010

Keywords

  • parabens
  • polymer
  • solid-phase extraction

Cite this

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title = "Synthetic approaches to parabens molecularly imprinted polymers and their applications to the solid-phase extraction of river water samples",
abstract = "Synthesis, characterization, and use of 2 distinct molecularly-imprinted polymers (MIP) prepd. using p-hydroxybenzoic acid (paraben) esters as templates are reported.: one MIP was synthesized by pptn. polymn. using a semi-covalent molecularly imprinting strategy with Me paraben as the template/target (MIP 1); the second MIP was prepd. in monolithic form through a conventional non-covalent mol. imprinting strategy, with Bu paraben as the template (MIP 2). One MIP was synthesized by pptn. polymn. using a semi-covalent molecularly imprinting strategy with Me paraben as the template/target (MIP 1); the second MIP was synthesized in monolithic form using a conventional, non-covalent mol. imprinting strategy with Bu paraben as the template (MIP 2). MIP 1 recognized Me paraben, showed cross-selectivity for other studied paraben analytes, and a higher affinity toward these compds. than a non-imprinted control polymer. Similarly, MIP 2 demonstrated a higher affinity toward paraben analytes than a non-imprinted control polymer. For anal. of environmental water, a solid phase extn. (SPE) protocol was developed using MIP 2 as sorbent; results were compared to SPE using a com. sorbent (Oasis HLB). With MIP 2 as sorbent and Bu paraben as target, when percolating 500 mL of river water spiked at 1 μg/L through the SPE cartridge, and using 1 mL of isopropanol as cleaning solvent, a higher Bu 4-hydroxybenzoate (Bu paraben) recovery and a cleaner chromatogram where achieved when using the MIP vs. the com. sorbent.",
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Synthetic approaches to parabens molecularly imprinted polymers and their applications to the solid-phase extraction of river water samples. / Beltran, A.; Marce, R. M.; Cormack, P. A. G.; Borrull, F.

In: Analytica Chimica Acta, Vol. 677, No. 1, 2010, p. 72-78.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Synthetic approaches to parabens molecularly imprinted polymers and their applications to the solid-phase extraction of river water samples

AU - Beltran, A.

AU - Marce, R. M.

AU - Cormack, P. A. G.

AU - Borrull, F.

PY - 2010

Y1 - 2010

N2 - Synthesis, characterization, and use of 2 distinct molecularly-imprinted polymers (MIP) prepd. using p-hydroxybenzoic acid (paraben) esters as templates are reported.: one MIP was synthesized by pptn. polymn. using a semi-covalent molecularly imprinting strategy with Me paraben as the template/target (MIP 1); the second MIP was prepd. in monolithic form through a conventional non-covalent mol. imprinting strategy, with Bu paraben as the template (MIP 2). One MIP was synthesized by pptn. polymn. using a semi-covalent molecularly imprinting strategy with Me paraben as the template/target (MIP 1); the second MIP was synthesized in monolithic form using a conventional, non-covalent mol. imprinting strategy with Bu paraben as the template (MIP 2). MIP 1 recognized Me paraben, showed cross-selectivity for other studied paraben analytes, and a higher affinity toward these compds. than a non-imprinted control polymer. Similarly, MIP 2 demonstrated a higher affinity toward paraben analytes than a non-imprinted control polymer. For anal. of environmental water, a solid phase extn. (SPE) protocol was developed using MIP 2 as sorbent; results were compared to SPE using a com. sorbent (Oasis HLB). With MIP 2 as sorbent and Bu paraben as target, when percolating 500 mL of river water spiked at 1 μg/L through the SPE cartridge, and using 1 mL of isopropanol as cleaning solvent, a higher Bu 4-hydroxybenzoate (Bu paraben) recovery and a cleaner chromatogram where achieved when using the MIP vs. the com. sorbent.

AB - Synthesis, characterization, and use of 2 distinct molecularly-imprinted polymers (MIP) prepd. using p-hydroxybenzoic acid (paraben) esters as templates are reported.: one MIP was synthesized by pptn. polymn. using a semi-covalent molecularly imprinting strategy with Me paraben as the template/target (MIP 1); the second MIP was prepd. in monolithic form through a conventional non-covalent mol. imprinting strategy, with Bu paraben as the template (MIP 2). One MIP was synthesized by pptn. polymn. using a semi-covalent molecularly imprinting strategy with Me paraben as the template/target (MIP 1); the second MIP was synthesized in monolithic form using a conventional, non-covalent mol. imprinting strategy with Bu paraben as the template (MIP 2). MIP 1 recognized Me paraben, showed cross-selectivity for other studied paraben analytes, and a higher affinity toward these compds. than a non-imprinted control polymer. Similarly, MIP 2 demonstrated a higher affinity toward paraben analytes than a non-imprinted control polymer. For anal. of environmental water, a solid phase extn. (SPE) protocol was developed using MIP 2 as sorbent; results were compared to SPE using a com. sorbent (Oasis HLB). With MIP 2 as sorbent and Bu paraben as target, when percolating 500 mL of river water spiked at 1 μg/L through the SPE cartridge, and using 1 mL of isopropanol as cleaning solvent, a higher Bu 4-hydroxybenzoate (Bu paraben) recovery and a cleaner chromatogram where achieved when using the MIP vs. the com. sorbent.

KW - parabens

KW - polymer

KW - solid-phase extraction

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M3 - Article

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JO - Analytica Chimica Acta

T2 - Analytica Chimica Acta

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