Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides

R. Brown; W.E. Smith; D. Graham

doi:10.1016/S0040-4039(02)02886-1

Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides

R. Brown, W.E. Smith, D. Graham

Pure And Applied Chemistry

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18 Citations (Scopus)

Abstract

The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman label for oligonucleotides that is capable of immobilisation of the oligonucleotide on metal surfaces such as silver nanoparticles. (C) 2003 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	1339-1342
Number of pages	3
Journal	Tetrahedron Letters
Volume	44
Issue number	7
DOIs	https://doi.org/10.1016/S0040-4039(02)02886-1
Publication status	Published - 10 Feb 2003

Keywords

resonance raman-scattering
nanoparticle probes
dna
serrs

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10.1016/S0040-4039(02)02886-1

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abstract = "The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman label for oligonucleotides that is capable of immobilisation of the oligonucleotide on metal surfaces such as silver nanoparticles. (C) 2003 Elsevier Science Ltd. All rights reserved.",

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AU - Brown, R.

AU - Smith, W.E.

AU - Graham, D.

PY - 2003/2/10

Y1 - 2003/2/10

N2 - The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman label for oligonucleotides that is capable of immobilisation of the oligonucleotide on metal surfaces such as silver nanoparticles. (C) 2003 Elsevier Science Ltd. All rights reserved.

AB - The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman label for oligonucleotides that is capable of immobilisation of the oligonucleotide on metal surfaces such as silver nanoparticles. (C) 2003 Elsevier Science Ltd. All rights reserved.

KW - resonance raman-scattering

KW - nanoparticle probes

KW - dna

KW - serrs

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DO - 10.1016/S0040-4039(02)02886-1

M3 - Article

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VL - 44

SP - 1339

EP - 1342

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 7

ER -

Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides

Abstract

Keywords

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