Abstract
The recent global increase in the abuse of 4-methylmethcathinone (mephedrone) and related compounds has developed a requirement for full chemical characterisation of these products. This work presents full synthetic and chemical characterisation data for the hydrobromide salts of two mephedrone derivatives: 4-methyl-N-ethylcathinone (4-MEC) and 4-methyl-N-benzylcathinone (4-MBC) which have been identified in samples of the “legal high” NRG-2. The first fully validated chromatographic methods for the detection and quantitative analysis of these substances both in their pure form and in the presence of a number of common adulterants used in illicit drug manufacture is also reported.
| Original language | English |
|---|---|
| Pages (from-to) | 122-135 |
| Number of pages | 14 |
| Journal | Journal of Pharmaceutical and Biomedical Analysis |
| Volume | 61 |
| DOIs | |
| Publication status | Published - 5 Mar 2012 |
Keywords
- NRG-2
- 4-methylmethcathinone
- mephedrone
- drugs
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Impacts
Illicit drug analysis as a tool to combat global organised crime
Niamh Nic Daeid (Participant), David Littlejohn (Participant), William Kerr (Participant), Oliver Brook Sutcliffe (Participant), Katy Savage (Participant) & W. Meier-Augenstein (Participant)
Impact: Impact - for External Portal › Quality of life and safety, Economic and commerce, Professional practice, training and standards