Synthesis, characterisation and multi-modal intracellular mapping of cisplatin nano-conjugates

Aristea Anna Leventi; Henry J. Braddick; Kharmen  Billimoria; Gregory Q. Wallace; Heidi Goenaga-Infante; Nicholas C.O. Tomkinson; Karen Faulds; Duncan Graham

doi:10.1039/d3cc00925d

Synthesis, characterisation and multi-modal intracellular mapping of cisplatin nano-conjugates

Aristea Anna Leventi, Henry J. Braddick, Kharmen Billimoria, Gregory Q. Wallace, Heidi Goenaga-Infante, Nicholas C.O. Tomkinson, Karen Faulds, Duncan Graham

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Abstract

The synthesis of nanocarriers for the delivery of the antitumor drug cisplatin is reported. Multimodal-imaging consisting of surface enhanced Raman scattering and laser ablation inductively coupled plasma time of flight mass spectrometry was used to visualise the intracellular uptake of both the nanocarrier and drug.

Original language	English
Pages (from-to)	6395-6398
Number of pages	4
Journal	Chemical Communications
Volume	59
Issue number	42
Early online date	9 May 2023
DOIs	https://doi.org/10.1039/d3cc00925d
Publication status	Published - 25 May 2023

Keywords

synthesis
characterisation
multi-modal intracellular mapping
cisplatin
nano-conjugates

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10.1039/d3cc00925dLicence: CC BY 3.0

Leventi-etal-CC-2023-Synthesis-characterisation-and-multi-modal-intracellular-mapping-of-cisplatinFinal published version, 1.45 MBLicence: CC BY 3.0

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title = "Synthesis, characterisation and multi-modal intracellular mapping of cisplatin nano-conjugates",

abstract = "The synthesis of nanocarriers for the delivery of the antitumor drug cisplatin is reported. Multimodal-imaging consisting of surface enhanced Raman scattering and laser ablation inductively coupled plasma time of flight mass spectrometry was used to visualise the intracellular uptake of both the nanocarrier and drug.",

keywords = "synthesis, characterisation, multi-modal intracellular mapping, cisplatin, nano-conjugates",

author = "Leventi, {Aristea Anna} and Braddick, {Henry J.} and Kharmen Billimoria and Wallace, {Gregory Q.} and Heidi Goenaga-Infante and Tomkinson, {Nicholas C.O.} and Karen Faulds and Duncan Graham",

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language = "English",

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AU - Leventi, Aristea Anna

AU - Braddick, Henry J.

AU - Billimoria, Kharmen

AU - Wallace, Gregory Q.

AU - Goenaga-Infante, Heidi

AU - Tomkinson, Nicholas C.O.

AU - Faulds, Karen

AU - Graham, Duncan

PY - 2023/5/25

Y1 - 2023/5/25

N2 - The synthesis of nanocarriers for the delivery of the antitumor drug cisplatin is reported. Multimodal-imaging consisting of surface enhanced Raman scattering and laser ablation inductively coupled plasma time of flight mass spectrometry was used to visualise the intracellular uptake of both the nanocarrier and drug.

AB - The synthesis of nanocarriers for the delivery of the antitumor drug cisplatin is reported. Multimodal-imaging consisting of surface enhanced Raman scattering and laser ablation inductively coupled plasma time of flight mass spectrometry was used to visualise the intracellular uptake of both the nanocarrier and drug.

KW - synthesis

KW - characterisation

KW - multi-modal intracellular mapping

KW - cisplatin

KW - nano-conjugates

UR - https://www.rsc.org/journals-books-databases/about-journals/chemcomm/

U2 - 10.1039/d3cc00925d

DO - 10.1039/d3cc00925d

M3 - Article

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VL - 59

SP - 6395

EP - 6398

JO - Chemical Communications

JF - Chemical Communications

IS - 42

ER -

Synthesis, characterisation and multi-modal intracellular mapping of cisplatin nano-conjugates

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Keywords

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Plasmonic Photothermal Heating of Gold Nanoparticles Increases Raman Scattering

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Synthesis, characterisation and multi-modal intracellular mapping of cisplatin nano-conjugates

Abstract

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Plasmonic Photothermal Heating of Gold Nanoparticles Increases Raman Scattering

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Data for: "Synthesis, characterization and multi-modal intracellular tracking of cisplatin nano-conjugates"

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