Susceptibility to African trypanosomiasis of Ndama and Zebu cattle in an area of glossina-morsitans-submorsitans challenge

M. Murray, D.J. Clifford, G. Gettinby, W.F. Snow, W.I.M. McIntyre

Research output: Contribution to journalArticle

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Abstract

The use of trypanotolerant livestock is considered to be an important strategy for the control of African animal trypanosomiasis. In order to define the extent of the differences in susceptibility and productivity, 10 Zebu cows (a breed considered trypanosusceptible) and 10 N'Dama cows (a breed recognised for trypanotolerance) were exposed to a natural field challenge from Glossina morsitans submorsitans Newstead. The animals were two-and-a-half to three years old and had not been previously exposed to trypanosomiasis. All Zebu died of trypanosomiasis within eight months of first exposure. In contrast, only three N'Dama died of trypanosomiasis; they had all been suckling calves before they succumbed 11 to 14 months after initial exposure. The prevalence, level and duration of parasitaemia were significantly less in the N'Dama, which, unlike the Zebu, did not become febrile during parasitaemia. The differences in parasitaemia were largely attributable to Trypanosoma vivax. The N'Dama also developed much less severe anaemia than the Zebu. The mean and standard deviation of the packed red cell volume of the N'Dama was not significantly different between eight months after exposure when all Zebu were dead, and 21 months when the experiment was terminated. The relative productivity of the N'Dama was impressive. In addition to reduced mortality, the N'Dama experienced no abortions and produced five calves, three of which were alive at the end of the experiment, at which time three of the surviving N'Dama were pregnant. In the Zebu, in marked contrast, abortions occurred both in early and late pregnancy and no live calves were produced. The study confirmed that N'Dama cattle are innately less susceptible to trypanosomiasis than Zebu cattle and can survive and be productive in endemic areas of trypanosomiasis where Zebu perish.
LanguageEnglish
Pages503-510
Number of pages7
JournalVeterinary Record
Volume109
Issue number23
Publication statusPublished - 1981

Fingerprint

Glossina morsitans submorsitans
African trypanosomiasis
N'dama
African Trypanosomiasis
Tsetse Flies
zebu
trypanosomiasis
Trypanosomiasis
cattle
parasitemia
Parasitemia
abortion (animals)
calves
trypanotolerance
Trypanosoma vivax
breeds
cows
suckling
Livestock
anemia

Keywords

  • African trypanosomiasis
  • Ndama
  • Zebu
  • cattle
  • glossina-morsitans-submorsitans

Cite this

Murray, M., Clifford, D. J., Gettinby, G., Snow, W. F., & McIntyre, W. I. M. (1981). Susceptibility to African trypanosomiasis of Ndama and Zebu cattle in an area of glossina-morsitans-submorsitans challenge. Veterinary Record, 109(23), 503-510.
Murray, M. ; Clifford, D.J. ; Gettinby, G. ; Snow, W.F. ; McIntyre, W.I.M. / Susceptibility to African trypanosomiasis of Ndama and Zebu cattle in an area of glossina-morsitans-submorsitans challenge. In: Veterinary Record. 1981 ; Vol. 109, No. 23. pp. 503-510.
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Murray, M, Clifford, DJ, Gettinby, G, Snow, WF & McIntyre, WIM 1981, 'Susceptibility to African trypanosomiasis of Ndama and Zebu cattle in an area of glossina-morsitans-submorsitans challenge' Veterinary Record, vol. 109, no. 23, pp. 503-510.

Susceptibility to African trypanosomiasis of Ndama and Zebu cattle in an area of glossina-morsitans-submorsitans challenge. / Murray, M.; Clifford, D.J.; Gettinby, G.; Snow, W.F.; McIntyre, W.I.M.

In: Veterinary Record, Vol. 109, No. 23, 1981, p. 503-510.

Research output: Contribution to journalArticle

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T1 - Susceptibility to African trypanosomiasis of Ndama and Zebu cattle in an area of glossina-morsitans-submorsitans challenge

AU - Murray, M.

AU - Clifford, D.J.

AU - Gettinby, G.

AU - Snow, W.F.

AU - McIntyre, W.I.M.

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N2 - The use of trypanotolerant livestock is considered to be an important strategy for the control of African animal trypanosomiasis. In order to define the extent of the differences in susceptibility and productivity, 10 Zebu cows (a breed considered trypanosusceptible) and 10 N'Dama cows (a breed recognised for trypanotolerance) were exposed to a natural field challenge from Glossina morsitans submorsitans Newstead. The animals were two-and-a-half to three years old and had not been previously exposed to trypanosomiasis. All Zebu died of trypanosomiasis within eight months of first exposure. In contrast, only three N'Dama died of trypanosomiasis; they had all been suckling calves before they succumbed 11 to 14 months after initial exposure. The prevalence, level and duration of parasitaemia were significantly less in the N'Dama, which, unlike the Zebu, did not become febrile during parasitaemia. The differences in parasitaemia were largely attributable to Trypanosoma vivax. The N'Dama also developed much less severe anaemia than the Zebu. The mean and standard deviation of the packed red cell volume of the N'Dama was not significantly different between eight months after exposure when all Zebu were dead, and 21 months when the experiment was terminated. The relative productivity of the N'Dama was impressive. In addition to reduced mortality, the N'Dama experienced no abortions and produced five calves, three of which were alive at the end of the experiment, at which time three of the surviving N'Dama were pregnant. In the Zebu, in marked contrast, abortions occurred both in early and late pregnancy and no live calves were produced. The study confirmed that N'Dama cattle are innately less susceptible to trypanosomiasis than Zebu cattle and can survive and be productive in endemic areas of trypanosomiasis where Zebu perish.

AB - The use of trypanotolerant livestock is considered to be an important strategy for the control of African animal trypanosomiasis. In order to define the extent of the differences in susceptibility and productivity, 10 Zebu cows (a breed considered trypanosusceptible) and 10 N'Dama cows (a breed recognised for trypanotolerance) were exposed to a natural field challenge from Glossina morsitans submorsitans Newstead. The animals were two-and-a-half to three years old and had not been previously exposed to trypanosomiasis. All Zebu died of trypanosomiasis within eight months of first exposure. In contrast, only three N'Dama died of trypanosomiasis; they had all been suckling calves before they succumbed 11 to 14 months after initial exposure. The prevalence, level and duration of parasitaemia were significantly less in the N'Dama, which, unlike the Zebu, did not become febrile during parasitaemia. The differences in parasitaemia were largely attributable to Trypanosoma vivax. The N'Dama also developed much less severe anaemia than the Zebu. The mean and standard deviation of the packed red cell volume of the N'Dama was not significantly different between eight months after exposure when all Zebu were dead, and 21 months when the experiment was terminated. The relative productivity of the N'Dama was impressive. In addition to reduced mortality, the N'Dama experienced no abortions and produced five calves, three of which were alive at the end of the experiment, at which time three of the surviving N'Dama were pregnant. In the Zebu, in marked contrast, abortions occurred both in early and late pregnancy and no live calves were produced. The study confirmed that N'Dama cattle are innately less susceptible to trypanosomiasis than Zebu cattle and can survive and be productive in endemic areas of trypanosomiasis where Zebu perish.

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