Accurate multiplex genotyping of the mutational status of the cystic fibrosis gene with the sensitive and selective SERRS technique is reported. This new assay does not require separation of the various alleles and shows that SERRS is a realistic alternative detection technique for use in modern DNA assays.
|Number of pages||2|
|Publication status||Published - 17 Dec 2001|
- DNA analysis
- nucleic acids
- Raman spectroscopy
- sequence determination
Graham, D., Mallinder, B. J., Whitcombe, D., & Smith, W. E. (2001). Surface enhanced resonance Raman scattering (SERRS) - a first example of its use in multiplex genotyping. ChemPhysChem, 2(12), 746-748. https://doi.org/10.1002/1439-7641(20011217)2:12<746::AID-CPHC746>3.0.CO;2-Q