Surface enhanced resonance Raman scattering (SERRS) - a first example of its use in multiplex genotyping

D. Graham, B.J. Mallinder, D. Whitcombe, W.E. Smith

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Accurate multiplex genotyping of the mutational status of the cystic fibrosis gene with the sensitive and selective SERRS technique is reported. This new assay does not require separation of the various alleles and shows that SERRS is a realistic alternative detection technique for use in modern DNA assays.
Original languageEnglish
Pages (from-to)746-748
Number of pages2
JournalChemPhysChem
Volume2
Issue number12
DOIs
Publication statusPublished - 17 Dec 2001

Keywords

  • colloids
  • DNA analysis
  • nucleic acids
  • Raman spectroscopy
  • sequence determination

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