Surface-enhanced Raman spectroscopy for in vivo biosensing

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Surface-enhanced Raman scattering (SERS) is of interest for biomedical analysis and imaging because of its sensitivity, specificity and multiplexing capabilities. The successful application of SERS for in vivo biosensing requires probes to be biocompatible and procedures to be minimally invasive, challenges that have respectively been met by developing new nanoprobes and instrumentation. This Review presents recent developments in these areas, describing case studies in which sensors have been implemented, as well as outlining shortcomings that must be addressed before SERS sees clinical use.

LanguageEnglish
Article number0060
Number of pages19
JournalNature Reviews Chemistry
Volume1
Early online date9 Aug 2017
DOIs
Publication statusE-pub ahead of print - 9 Aug 2017

Fingerprint

Raman spectroscopy
Raman scattering
Nanoprobes
Multiplexing
Imaging techniques
Sensors

Keywords

  • surface enhanced Raman scattering
  • biosensing
  • in vitro

Cite this

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Surface-enhanced Raman spectroscopy for in vivo biosensing. / Laing, Stacey; Jamieson, Lauren E.; Faulds, Karen; Graham, Duncan.

In: Nature Reviews Chemistry, Vol. 1, 0060, 09.08.2017.

Research output: Contribution to journalArticle

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