Surface enhanced Raman scattering for multiplexed detection

Jennifer A. Dougan, Karen Faulds

Research output: Contribution to journalLiterature review

81 Citations (Scopus)

Abstract

The multiplexed detection of biological analytes from complex mixtures is of crucial importance for the future of intelligent management and detection of disease. This review focuses on recent advances in the use of surface enhanced Raman scattering (SERS) spectroscopy as an analytical technique that can deliver multiplexed detection for a variety of biological target in increasingly complex media. The use of SERS has developed from the multipelxed detection of custom dye molecules to biomolecules such as DNA and proteins. Recent work has also shown the capability of SERS multiplexing for in vivo as well as in vitro applications.

Original languageEnglish
Pages (from-to)545-554
Number of pages10
JournalAnalyst
Volume137
Issue number3
DOIs
Publication statusPublished - 2012

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Keywords

  • disease detection
  • Raman scattering
  • multiplexed detection

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