Supramolecular Au nanoparticle assemblies as optical probes for enzyme-linked immunoassays

Roberto De La Rica, Aldrik Velders

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A novel enzyme-linked immunoassay with nanoparticle assemblies as optical probes is presented. The macrocycle cucurbit[7]uril assembles gold nanoparticles, and the enzymatic generation of ammonium by urease as the label of the immunoassay disperses the probes to yield variations of plasmon absorbance that are proportional to the target protein concentration.
Original languageEnglish
Pages (from-to)66–69
Number of pages4
JournalSmall
Volume7
Issue number1
Early online date22 Nov 2010
DOIs
Publication statusPublished - 3 Jan 2011

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Keywords

  • sensors
  • nanoparticles
  • bionanotechnology
  • cucurbituril
  • nanosensors

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