Supramolecular Au nanoparticle assemblies as optical probes for enzyme-linked immunoassays

Roberto De La Rica, Aldrik Velders

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A novel enzyme-linked immunoassay with nanoparticle assemblies as optical probes is presented. The macrocycle cucurbit[7]uril assembles gold nanoparticles, and the enzymatic generation of ammonium by urease as the label of the immunoassay disperses the probes to yield variations of plasmon absorbance that are proportional to the target protein concentration.
LanguageEnglish
Pages66–69
Number of pages4
JournalSmall
Volume7
Issue number1
Early online date22 Nov 2010
DOIs
Publication statusPublished - 3 Jan 2011

Fingerprint

immunoassay
Immunoenzyme Techniques
Nanoparticles
assemblies
enzymes
Enzymes
nanoparticles
Urease
probes
Ammonium Compounds
Immunoassay
Gold
Labels
gold
proteins
Proteins
cucurbit(7)uril

Keywords

  • sensors
  • nanoparticles
  • bionanotechnology
  • cucurbituril
  • nanosensors

Cite this

De La Rica, Roberto ; Velders, Aldrik. / Supramolecular Au nanoparticle assemblies as optical probes for enzyme-linked immunoassays. In: Small. 2011 ; Vol. 7, No. 1. pp. 66–69.
@article{05b142c9c612462e84bdd00f9b657ad6,
title = "Supramolecular Au nanoparticle assemblies as optical probes for enzyme-linked immunoassays",
abstract = "A novel enzyme-linked immunoassay with nanoparticle assemblies as optical probes is presented. The macrocycle cucurbit[7]uril assembles gold nanoparticles, and the enzymatic generation of ammonium by urease as the label of the immunoassay disperses the probes to yield variations of plasmon absorbance that are proportional to the target protein concentration.",
keywords = "sensors, nanoparticles, bionanotechnology, cucurbituril, nanosensors",
author = "{De La Rica}, Roberto and Aldrik Velders",
year = "2011",
month = "1",
day = "3",
doi = "10.1002/smll.201001340",
language = "English",
volume = "7",
pages = "66–69",
journal = "Small",
issn = "1613-6810",
number = "1",

}

Supramolecular Au nanoparticle assemblies as optical probes for enzyme-linked immunoassays. / De La Rica, Roberto; Velders, Aldrik.

In: Small, Vol. 7, No. 1, 03.01.2011, p. 66–69.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Supramolecular Au nanoparticle assemblies as optical probes for enzyme-linked immunoassays

AU - De La Rica, Roberto

AU - Velders, Aldrik

PY - 2011/1/3

Y1 - 2011/1/3

N2 - A novel enzyme-linked immunoassay with nanoparticle assemblies as optical probes is presented. The macrocycle cucurbit[7]uril assembles gold nanoparticles, and the enzymatic generation of ammonium by urease as the label of the immunoassay disperses the probes to yield variations of plasmon absorbance that are proportional to the target protein concentration.

AB - A novel enzyme-linked immunoassay with nanoparticle assemblies as optical probes is presented. The macrocycle cucurbit[7]uril assembles gold nanoparticles, and the enzymatic generation of ammonium by urease as the label of the immunoassay disperses the probes to yield variations of plasmon absorbance that are proportional to the target protein concentration.

KW - sensors

KW - nanoparticles

KW - bionanotechnology

KW - cucurbituril

KW - nanosensors

U2 - 10.1002/smll.201001340

DO - 10.1002/smll.201001340

M3 - Article

VL - 7

SP - 66

EP - 69

JO - Small

T2 - Small

JF - Small

SN - 1613-6810

IS - 1

ER -