Abstract
A novel enzyme-linked immunoassay with nanoparticle assemblies as optical probes is presented. The macrocycle cucurbit[7]uril assembles gold nanoparticles, and the enzymatic generation of ammonium by urease as the label of the immunoassay disperses the probes to yield variations of plasmon absorbance that are proportional to the target protein concentration.
| Original language | English |
|---|---|
| Pages (from-to) | 66–69 |
| Number of pages | 4 |
| Journal | Small |
| Volume | 7 |
| Issue number | 1 |
| Early online date | 22 Nov 2010 |
| DOIs | |
| Publication status | Published - 3 Jan 2011 |
Keywords
- sensors
- nanoparticles
- bionanotechnology
- cucurbituril
- nanosensors