Structure and activities of pharmacy and therapeutics committees among public hospitals in South Africa: findings and implications

Moliehi Matlala, Andries GS Gous, Brian Godman, Johanna C Meyer

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Introduction: The WHO identified Pharmacy and Therapeutics Committees (PTCs) as a pivotal model to promote rational medicine use in hospitals. This matches a key South African (SA) government objective to establish PTCs in all hospitals to ensure rational, efficient and cost-effective use of medicines. However, documentation on the functionality of PTCs in public hospitals in SA is limited. This study aimed to address this. Methods: A 3-phased mixed methods approach involving questionnaires, observations of PTC meetings and semi-structured interviews. The findings were converged during the interpretation phase. Results: Most professionals were represented in the PTCs, with variations across hospitals. Membership of PTCs included a pharmacist, who in the majority of cases was the secretary. PTC activities included dissemination of decisions (100%) and formulary management (89.5%). However, reporting of ADRs and medication errors was typically poor at all hospital levels. Lack of expertise of pharmacoeconomic analysis and evidence-based decision-making in formulary management was identified as a key challenge in formulary management. Conclusion: Future programmes should strengthen PTCs in specialised aspects of formulary management. Further training in the principles of pharmacovigilance is needed at all levels to enhance ADR reporting, as well as to ensure compliance with both WHO and provincial guidelines.
LanguageEnglish
Pages1273-1280
Number of pages8
JournalExpert Review of Clinical Pharmacology
Volume10
Issue number11
Early online date4 Aug 2017
DOIs
Publication statusPublished - 16 Aug 2017

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Pharmacy and Therapeutics Committee
Public Hospitals
South Africa
Formularies
Pharmacovigilance
Pharmaceutical Economics
Medication Errors
Pharmacists
Documentation
Decision Making
Medicine
Guidelines
Interviews
Costs and Cost Analysis

Keywords

  • pharmacy and therapeutic committees
  • hospitals
  • rational use of medicines
  • pharmacovigilance
  • South Africa

Cite this

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abstract = "Introduction: The WHO identified Pharmacy and Therapeutics Committees (PTCs) as a pivotal model to promote rational medicine use in hospitals. This matches a key South African (SA) government objective to establish PTCs in all hospitals to ensure rational, efficient and cost-effective use of medicines. However, documentation on the functionality of PTCs in public hospitals in SA is limited. This study aimed to address this. Methods: A 3-phased mixed methods approach involving questionnaires, observations of PTC meetings and semi-structured interviews. The findings were converged during the interpretation phase. Results: Most professionals were represented in the PTCs, with variations across hospitals. Membership of PTCs included a pharmacist, who in the majority of cases was the secretary. PTC activities included dissemination of decisions (100{\%}) and formulary management (89.5{\%}). However, reporting of ADRs and medication errors was typically poor at all hospital levels. Lack of expertise of pharmacoeconomic analysis and evidence-based decision-making in formulary management was identified as a key challenge in formulary management. Conclusion: Future programmes should strengthen PTCs in specialised aspects of formulary management. Further training in the principles of pharmacovigilance is needed at all levels to enhance ADR reporting, as well as to ensure compliance with both WHO and provincial guidelines.",
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Structure and activities of pharmacy and therapeutics committees among public hospitals in South Africa : findings and implications. / Matlala, Moliehi ; Gous, Andries GS; Godman, Brian; Meyer, Johanna C.

In: Expert Review of Clinical Pharmacology, Vol. 10, No. 11, 16.08.2017, p. 1273-1280.

Research output: Contribution to journalArticle

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