Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data

Zsuzsanna Orbán-Németh, Rebecca Beveridge, David M Hollenstein, Evelyn Rampler, Thomas Stranzl, Otto Hudecz, Johannes Doblmann, Peter Schlögelhofer, Karl Mechtler

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

This protocol describes how to use distance restraints obtained from cross-linking mass spectrometry (XL-MS) experiments to guide the structural prediction of proteins and protein complexes.
Original languageEnglish
Pages (from-to)478-494
Number of pages17
JournalNature Protocols
Volume13
Issue number3
Early online date8 Feb 2018
DOIs
Publication statusPublished - 25 Jun 2018

Keywords

  • proteins
  • protein complexes
  • mass spectrometry

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