Structural instability in an autophosphorylating kinase switch

M. Grinfeld, S.D. Webb

Research output: Contribution to journalArticle

1 Citation (Scopus)
50 Downloads (Pure)

Abstract

We analyse a simple kinase model that exhibits bistability when there is no protein turnover, and show analytically that the property of being bistable is not necessarily conserved when degradation and synthesis of the kinase are taken into account.
Original languageEnglish
Pages (from-to)92-96
Number of pages5
JournalMathematical Biosciences
Volume219
Issue number2
DOIs
Publication statusPublished - Jun 2009

Keywords

  • bistability
  • protein turnover
  • structural instability
  • numerical mathematics
  • statistics

Fingerprint Dive into the research topics of 'Structural instability in an autophosphorylating kinase switch'. Together they form a unique fingerprint.

  • Cite this