TY - JOUR
T1 - Structural information on nanomolecular systems revealed by FRET
AU - Rolinski, Olaf J.
AU - Mathivanan, Chinnaraj
AU - McNaught, Gillian
AU - Birch, David J.S.
PY - 2004/5/25
Y1 - 2004/5/25
N2 - Our newly developed fluorescence resonance energy transfer (FRET) based technique, fluorescence nanotomography (FN), is used to determine the morphology and dynamics of some soft materials and bio-molecules by attaching donor (D) fluorophores and acceptors (A) to the investigated structure and using fluorescence lifetime measurements to reveal the D-A distance distribution function ρDA(r).We report the effect of the limited sizes of the donor and acceptor, effect of porous polymer, and molecular structure and phase transition in phospholipid bilayers.
AB - Our newly developed fluorescence resonance energy transfer (FRET) based technique, fluorescence nanotomography (FN), is used to determine the morphology and dynamics of some soft materials and bio-molecules by attaching donor (D) fluorophores and acceptors (A) to the investigated structure and using fluorescence lifetime measurements to reveal the D-A distance distribution function ρDA(r).We report the effect of the limited sizes of the donor and acceptor, effect of porous polymer, and molecular structure and phase transition in phospholipid bilayers.
KW - nanomolecular systems
KW - FRET
KW - fluorescence nanotomography
KW - nanoscience
UR - http://dx.doi.org/10.1016/j.bios.2004.02.031
U2 - 10.1016/j.bios.2004.02.031
DO - 10.1016/j.bios.2004.02.031
M3 - Article
SN - 0956-5663
VL - 20
SP - 424
EP - 430
JO - Biosensors and Bioelectronics
JF - Biosensors and Bioelectronics
IS - 3
ER -