Abstract
This study explores whether self-reported depth of hypnosis and hypnotic suggestibility are associated with individual differences in neuroanatomy and/or levels of functional connectivity. Twenty-nine people varying in suggestibility were recruited and underwent structural, and after a hypnotic induction, functional magnetic resonance imaging at rest. We used voxel-based morphometry to assess the correlation of grey matter (GM) and white matter (WM) against the independent variables: depth of hypnosis, level of relaxation and hypnotic suggestibility. Functional networks identified with independent components analysis were regressed with the independent variables. Hypnotic depth ratings were positively correlated with GM volume in the frontal cortex and the anterior cingulate cortex (ACC). Hypnotic suggestibility was positively correlated with GM volume in the left temporal-occipital cortex. Relaxation ratings did not correlate significantly with GM volume and none of the independent variables correlated with regional WM volume measures. Self-reported deeper levels of hypnosis were associated with less connectivity within the anterior default mode network. Taken together, the results suggest that the greater GM volume in the medial frontal cortex and ACC, and lower connectivity in the DMN during hypnosis facilitate experiences of greater hypnotic depth. The patterns of results suggest that hypnotic depth and hypnotic suggestibility should not be considered synonyms.
| Language | English |
|---|---|
| Pages | 151-159 |
| Number of pages | 9 |
| Journal | Psychiatry Research |
| Volume | 231 |
| Issue number | 2 |
| Early online date | 6 Dec 2014 |
| DOIs | |
| Publication status | Published - 28 Feb 2015 |
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Keywords
- hypnosis
- susceptibility
- voxel-based morphometry;
- grey matter
- white matter
- functional connectivity
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Structural and functional correlates of hypnotic depth and suggestibility. / McGeown, William Jonathan; Mazzoni, Giuliana; Vannucci, Manila; Venneri, Annalena.
In: Psychiatry Research, Vol. 231, No. 2, 28.02.2015, p. 151-159.Research output: Contribution to journal › Article
TY - JOUR
T1 - Structural and functional correlates of hypnotic depth and suggestibility
AU - McGeown, William Jonathan
AU - Mazzoni, Giuliana
AU - Vannucci, Manila
AU - Venneri, Annalena
PY - 2015/2/28
Y1 - 2015/2/28
N2 - This study explores whether self-reported depth of hypnosis and hypnotic suggestibility are associated with individual differences in neuroanatomy and/or levels of functional connectivity. Twenty-nine people varying in suggestibility were recruited and underwent structural, and after a hypnotic induction, functional magnetic resonance imaging at rest. We used voxel-based morphometry to assess the correlation of grey matter (GM) and white matter (WM) against the independent variables: depth of hypnosis, level of relaxation and hypnotic suggestibility. Functional networks identified with independent components analysis were regressed with the independent variables. Hypnotic depth ratings were positively correlated with GM volume in the frontal cortex and the anterior cingulate cortex (ACC). Hypnotic suggestibility was positively correlated with GM volume in the left temporal-occipital cortex. Relaxation ratings did not correlate significantly with GM volume and none of the independent variables correlated with regional WM volume measures. Self-reported deeper levels of hypnosis were associated with less connectivity within the anterior default mode network. Taken together, the results suggest that the greater GM volume in the medial frontal cortex and ACC, and lower connectivity in the DMN during hypnosis facilitate experiences of greater hypnotic depth. The patterns of results suggest that hypnotic depth and hypnotic suggestibility should not be considered synonyms.
AB - This study explores whether self-reported depth of hypnosis and hypnotic suggestibility are associated with individual differences in neuroanatomy and/or levels of functional connectivity. Twenty-nine people varying in suggestibility were recruited and underwent structural, and after a hypnotic induction, functional magnetic resonance imaging at rest. We used voxel-based morphometry to assess the correlation of grey matter (GM) and white matter (WM) against the independent variables: depth of hypnosis, level of relaxation and hypnotic suggestibility. Functional networks identified with independent components analysis were regressed with the independent variables. Hypnotic depth ratings were positively correlated with GM volume in the frontal cortex and the anterior cingulate cortex (ACC). Hypnotic suggestibility was positively correlated with GM volume in the left temporal-occipital cortex. Relaxation ratings did not correlate significantly with GM volume and none of the independent variables correlated with regional WM volume measures. Self-reported deeper levels of hypnosis were associated with less connectivity within the anterior default mode network. Taken together, the results suggest that the greater GM volume in the medial frontal cortex and ACC, and lower connectivity in the DMN during hypnosis facilitate experiences of greater hypnotic depth. The patterns of results suggest that hypnotic depth and hypnotic suggestibility should not be considered synonyms.
KW - hypnosis
KW - susceptibility
KW - voxel-based morphometry;
KW - grey matter
KW - white matter
KW - functional connectivity
UR - http://www.sciencedirect.com/science/journal/aip/09254927
U2 - 10.1016/j.pscychresns.2014.11.015
DO - 10.1016/j.pscychresns.2014.11.015
M3 - Article
VL - 231
SP - 151
EP - 159
JO - Psychiatry Research
T2 - Psychiatry Research
JF - Psychiatry Research
SN - 0165-1781
IS - 2
ER -