Stent design for gastrointestinal leakage

R.A. Rothwell, M.S. Pridham, G.A. Thomson

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Abstract

    Stents are largely used to counteract and relieve duct or vessel obstructions. The purpose of this current study is to select a biodegradable, antibacterial and environmentally friendly material to design and prepare a stent to counteract anastomotic leakage following gastrointestinal surgery. A precast moulding process was used to prepare medium molecular weight chitosan scaffolds, for stent design. Chitosan samples were prepared by opening the bonds of the material in acetic acid, moulding the material and curing the mouldings in sodium hydroxide. The film like mouldings were wound around a metallic rod, fixing the layers together with un-cured chitosan and subsequently curing the chitosan layers together with sodium hydroxide producing the stent like shape. Tensile and tensile creep strength of the chitosan material was investigated. This research concluded that chitosan can be moulded into a stent like geometry. Mechanical testing showed the tensile and tensile creep strength were repeatable and could be predetermined. This indicates that chitosan is a suitable material for the further development of a biodegradable stent designed to counteract gastrointestinal leakage.
    LanguageEnglish
    Pages2169-2172
    Number of pages3
    JournalIFMBE Proceedings
    Volume22
    Issue number17
    DOIs
    Publication statusPublished - 4 Feb 2009

    Fingerprint

    Stents
    Chitosan
    Molding
    Sodium Hydroxide
    Curing
    Creep
    Sodium
    Mechanical testing
    Acetic acid
    Scaffolds
    Acetic Acid
    Ducts
    Surgery
    Molecular weight
    Geometry

    Keywords

    • stent design
    • orthotics
    • prosthetics
    • heart
    • gastrointestinal system

    Cite this

    Rothwell, R. A., Pridham, M. S., & Thomson, G. A. (2009). Stent design for gastrointestinal leakage. IFMBE Proceedings , 22(17), 2169-2172. https://doi.org/10.1007/978-3-540-89208-3_518
    Rothwell, R.A. ; Pridham, M.S. ; Thomson, G.A. / Stent design for gastrointestinal leakage. In: IFMBE Proceedings . 2009 ; Vol. 22, No. 17. pp. 2169-2172.
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    Rothwell, RA, Pridham, MS & Thomson, GA 2009, 'Stent design for gastrointestinal leakage' IFMBE Proceedings , vol. 22, no. 17, pp. 2169-2172. https://doi.org/10.1007/978-3-540-89208-3_518

    Stent design for gastrointestinal leakage. / Rothwell, R.A.; Pridham, M.S.; Thomson, G.A.

    In: IFMBE Proceedings , Vol. 22, No. 17, 04.02.2009, p. 2169-2172.

    Research output: Contribution to journalArticle

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    Rothwell RA, Pridham MS, Thomson GA. Stent design for gastrointestinal leakage. IFMBE Proceedings . 2009 Feb 4;22(17):2169-2172. https://doi.org/10.1007/978-3-540-89208-3_518