Static mode microfluidic cantilevers for detection of waterborne pathogens

Helen Bridle, Wenxing Wang, Despoina Gavriilidou, Farid Amalou, Duncan P. Hand, Wenmiao Shu

Research output: Contribution to journalArticle

10 Citations (Scopus)
62 Downloads (Pure)

Abstract

This paper reports on the first demonstration of polymeric microfluidic cantilever sensors. Microcantilever sensors, magnetic beads, and microfluidic technology have been combined to create a polymer based biosensor. Using cheap materials like polyimide, a simple fabrication method has been developed to produce cantilevers with an embedded microfluidic channel. The advantage of this approach is that the addition of a microfluidic channel enables the analysis of smaller volumes and increases the capture efficiency in applications detecting rare analytes. As a proof of principle the system has been applied for the detection of the waterborne protozoan parasite Cryptosporidium, achieving sensitivity comparable to QCM, whereas a previous set-up without the microfluidic channel was unable to detect the parasite.
Original languageEnglish
Pages (from-to)144-149
Number of pages6
JournalSensors and Actuators A: Physical
Volume247
Early online date6 May 2016
DOIs
Publication statusE-pub ahead of print - 6 May 2016

Keywords

  • microfluidics
  • cantilever
  • cryptosporidium
  • detection

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