@article{8ab91224b16046a3bb40a73e8418bd4a,
title = "Speciation control during Suzuki-Miyaura cross-coupling of haloaryl and haloalkenyl MIDA boronic esters",
abstract = "Boronic acid solution speciation can be controlled during the Suzuki-Miyaura cross-coupling of haloaryl MIDA boronic esters to enable the formal homologation of boronic acid derivatives. The reaction is contingent upon control of the basic biphase and is thermodynamically driven: temperature control provides highly chemoselective access to either BMIDA adducts at room temperature or BPin products at elevated temperature. Control experiments and solubility analyses have provided some insight into the mechanistic operation of the formal homologation process.",
keywords = "boron, chemoselectivity, cross-coupling, palladium, speciation",
author = "Fyfe, {James W. B.} and Elena Valverde and Seath, {Ciaran P.} and Kennedy, {Alan R.} and Redmond, {Joanna M.} and Anderson, {Niall A.} and Watson, {Allan J. B.}",
note = " This is the peer reviewed version of the following article: Fyfe, J. W. B., Valverde, E., Seath, C. P., Kennedy, A. R., Redmond, J. M., Anderson, N. A., & Watson, A. J. B. (2015). Speciation control during Suzuki-Miyaura cross-coupling of haloaryl and haloalkenyl MIDA boronic esters. Chemistry - A European Journal, 21(24), 8951–8964, which has been published in final form at http://dx.doi.org/10.1002/chem.201500970 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving",
year = "2015",
month = jun,
day = "8",
doi = "10.1002/chem.201500970",
language = "English",
volume = "21",
pages = "8951–8964",
journal = "Chemistry - A European Journal",
issn = "0947-6539",
number = "24",
}