Solution co-crystallisation and its applications

Tom Leyssens, Joop H. ter Horst

Research output: Chapter in Book/Report/Conference proceedingChapter

  • 1 Citations

Abstract

Even though the term co-crystal remains topic of debate, general consensus evolves towards defining co-crystals as crystalline compounds constructed of 2 or more neutral components which are, in their pure form, solid at room temperature and under atmospheric pressure. In most cases this definition clearly distinguishes co-crystals from salts or solvates. For solvates one of the components in its pure form, the solvent, is a liquid. A co-crystal is different from a salt since it is constructed from two distinct neutral components without any charge transfer taking place between components. Co-crystals can therefore be formed of components that lack ionizable functional groups.
LanguageEnglish
Title of host publicationMulti-Component Crystals
Subtitle of host publicationSynthesis, Concepts, Function
EditorsEdward R T Tiekink, Julio Zukerman-Schpector
Place of PublicationBerlin
PublisherWalter de Gruyter GmbH
Chapter9
Pages205-236
Number of pages32
ISBN (Print)9783110463651
DOIs
StatePublished - 23 Nov 2017

Fingerprint

Crystallization
Crystals
Salts
Functional groups
Atmospheric pressure
Charge transfer
Crystalline materials
Liquids
Temperature

Keywords

  • co-crystals
  • salts
  • solvents
  • crystal solutions

Cite this

Leyssens, T., & ter Horst, J. H. (2017). Solution co-crystallisation and its applications. In E. R. T. Tiekink, & J. Zukerman-Schpector (Eds.), Multi-Component Crystals: Synthesis, Concepts, Function (pp. 205-236). Berlin: Walter de Gruyter GmbH. DOI: 10.1515/9783110464955-009
Leyssens, Tom ; ter Horst, Joop H./ Solution co-crystallisation and its applications. Multi-Component Crystals: Synthesis, Concepts, Function. editor / Edward R T Tiekink ; Julio Zukerman-Schpector. Berlin : Walter de Gruyter GmbH, 2017. pp. 205-236
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Leyssens, T & ter Horst, JH 2017, Solution co-crystallisation and its applications. in ERT Tiekink & J Zukerman-Schpector (eds), Multi-Component Crystals: Synthesis, Concepts, Function. Walter de Gruyter GmbH, Berlin, pp. 205-236. DOI: 10.1515/9783110464955-009

Solution co-crystallisation and its applications. / Leyssens, Tom; ter Horst, Joop H.

Multi-Component Crystals: Synthesis, Concepts, Function. ed. / Edward R T Tiekink; Julio Zukerman-Schpector. Berlin : Walter de Gruyter GmbH, 2017. p. 205-236.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Leyssens T, ter Horst JH. Solution co-crystallisation and its applications. In Tiekink ERT, Zukerman-Schpector J, editors, Multi-Component Crystals: Synthesis, Concepts, Function. Berlin: Walter de Gruyter GmbH. 2017. p. 205-236. Available from, DOI: 10.1515/9783110464955-009