Small molecule analogues of the parasitic worm product ES-62 interact with the TIR domain of MyD88 to inhibit pro-inflammatory signalling

Colin J. Suckling
, Shahabuddin Alam
, Mark A. Olson
, Kamal U. Saikh
, Margaret M. Harnett
, William Harnett

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

68 Downloads (Pure)

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The Filarial Nematode Immunomodulator Es-62 As A Tool In Novel Drug Development For Mast Cell-Dependent Inflammatory Diseases
Harnett, W. (Principal Investigator)
Wellcome Trust
1/05/09 → 31/08/15
Project: Research
SMALL MOLECULE ANALOGUES (SMA'S) OF AN IMMUNOMDULATORY HELMINTH PRODUCT PROVIDE A NOVEL APPROACH TO DISSECTING MACROPHAGE SIGNAL TRANDUCTION PATHWAYS
Harnett, W. (Principal Investigator) & Suckling, C. (Co-investigator)
BBSRC (Biotech & Biological Sciences Research Council)
1/05/07 → 31/12/10
Project: Research