Site-specific assembly of DNA-based photonic wires by using programmable polyamides

Wu Su, Markus Schuster, Clive R Bagshaw, Ulrich Rant, Glenn Burley

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The first example of a programmable DNA photonic wire is reported utilizing fluorophore-tethered pyrrole-imidazole polyamides for site-directed fluorophore assembly along a pre-formed DNA duplex (see scheme; PB=Pacific Blue, Cy3=Cyanine 3; orange rectangles=fluorophore). The importance of such control is revealed by efficient energy transport over distances in excess of 27 nm.
Original languageEnglish
Pages (from-to)2712-2715
Number of pages4
JournalAngewandte Chemie
Volume50
Issue number12
Early online date25 Feb 2011
DOIs
Publication statusPublished - 14 Mar 2011

Keywords

  • DNA
  • polyamides
  • photonic wire
  • minor groove
  • energy transfer

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