Site-specific assembly of DNA-based photonic wires by using programmable polyamides

Wu Su; Markus Schuster; Clive R Bagshaw; Ulrich Rant; Glenn Burley

doi:10.1002/anie.201006735

Site-specific assembly of DNA-based photonic wires by using programmable polyamides

Wu Su, Markus Schuster, Clive R Bagshaw, Ulrich Rant, Glenn Burley

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

The first example of a programmable DNA photonic wire is reported utilizing fluorophore-tethered pyrrole-imidazole polyamides for site-directed fluorophore assembly along a pre-formed DNA duplex (see scheme; PB=Pacific Blue, Cy3=Cyanine 3; orange rectangles=fluorophore). The importance of such control is revealed by efficient energy transport over distances in excess of 27 nm.

Original language	English
Pages (from-to)	2712-2715
Number of pages	4
Journal	Angewandte Chemie
Volume	50
Issue number	12
Early online date	25 Feb 2011
DOIs	https://doi.org/10.1002/anie.201006735
Publication status	Published - 14 Mar 2011

Keywords

DNA
polyamides
photonic wire
minor groove
energy transfer

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10.1002/anie.201006735

1 Finished
1 Active

JARL Start Up Funding
Burley, G.
1/06/11 → …
Project: Internally funded project
New Molecular Tools For The 21st Century: Molecular Design Of New DNA-Based Devices
Burley, G.
EPSRC (Engineering and Physical Sciences Research Council)
1/04/12 → 31/03/13
Project: Research Fellowship

Cite this

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title = "Site-specific assembly of DNA-based photonic wires by using programmable polyamides",

abstract = " The first example of a programmable DNA photonic wire is reported utilizing fluorophore-tethered pyrrole-imidazole polyamides for site-directed fluorophore assembly along a pre-formed DNA duplex (see scheme; PB=Pacific Blue, Cy3=Cyanine 3; orange rectangles=fluorophore). The importance of such control is revealed by efficient energy transport over distances in excess of 27 nm.",

keywords = "DNA, polyamides , photonic wire, minor groove, energy transfer",

author = "Wu Su and Markus Schuster and Bagshaw, {Clive R} and Ulrich Rant and Glenn Burley",

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AU - Su, Wu

AU - Schuster, Markus

AU - Bagshaw, Clive R

AU - Rant, Ulrich

AU - Burley, Glenn

PY - 2011/3/14

Y1 - 2011/3/14

N2 - The first example of a programmable DNA photonic wire is reported utilizing fluorophore-tethered pyrrole-imidazole polyamides for site-directed fluorophore assembly along a pre-formed DNA duplex (see scheme; PB=Pacific Blue, Cy3=Cyanine 3; orange rectangles=fluorophore). The importance of such control is revealed by efficient energy transport over distances in excess of 27 nm.

AB - The first example of a programmable DNA photonic wire is reported utilizing fluorophore-tethered pyrrole-imidazole polyamides for site-directed fluorophore assembly along a pre-formed DNA duplex (see scheme; PB=Pacific Blue, Cy3=Cyanine 3; orange rectangles=fluorophore). The importance of such control is revealed by efficient energy transport over distances in excess of 27 nm.

KW - DNA

KW - polyamides

KW - photonic wire

KW - minor groove

KW - energy transfer

U2 - 10.1002/anie.201006735

DO - 10.1002/anie.201006735

M3 - Article

VL - 50

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JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

SN - 1433-7851

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ER -

Site-specific assembly of DNA-based photonic wires by using programmable polyamides

Abstract

Keywords

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Projects

JARL Start Up Funding

New Molecular Tools For The 21st Century: Molecular Design Of New DNA-Based Devices

Cite this