Single cell mobility adhesion monitoring using extracellular electrodes

R. Lind, P. Connolly, C.D.W. Wilkinson, L. Breckenridge, J.A.T. Dow

    Research output: Contribution to journalArticle

    41 Citations (Scopus)

    Abstract

    Cell attachment and activity on planar electrodes can be observed in real time by continuously monitoring the electrode impedance. The application of a low frequency a.c. field affects neither the electrode properties nor cell growth. The tightness of the cell/electrode junction can be quantified, and has been shown to be dependent on both cell type and electrode surface. Studies have been carried out on both large cell populations, and the single cell/microelectrode interface.
    Original languageEnglish
    Pages (from-to)359-367
    Number of pages8
    JournalBiosensors and Bioelectronics
    Volume6
    Issue number4
    Publication statusPublished - 1991

    Keywords

    • impedance
    • electrodes
    • microelectrodes
    • cell
    • neuron
    • fibroblast
    • mobility
    • adhesion

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  • Cite this

    Lind, R., Connolly, P., Wilkinson, C. D. W., Breckenridge, L., & Dow, J. A. T. (1991). Single cell mobility adhesion monitoring using extracellular electrodes. Biosensors and Bioelectronics, 6(4), 359-367.