Simulating drug-eluting stents: progress made and the way forward

Sean McGinty, Christopher McCormick, Sean McKee, Marcus Wheel, Simon Kennedy, Keith G. Oldroyd

Research output: Contribution to conferencePaper

Abstract

Drug-eluting stents have significantly improved the treatment of coronary artery disease. Compared with their bare metal predecessors, they offer reduced rates of restenosis and thus represent the current gold standard in percutaneous coronary interventions. Drug-eluting stents have been around for over a decade, and while progress is continually being made, they are not suitable in all patients and lesion types. Furthermore there are still real concerns over incomplete healing and late stent thrombosis. In this paper, some modelling approaches are reviewed and the future of modelling and simulation in this field is discussed.

Conference

ConferenceSpecial Session on Modelling and Simulation in Biology and Medicine (BIOMED 2013)
CountryIceland
CityReykajvik
Period29/07/1331/07/13

Fingerprint

Stent
Drugs
Restenosis
Thrombosis
Coronary Artery Disease
Gold
Modeling and Simulation
Metals
Modeling

Keywords

  • drug-eluting stents
  • coronary artery disease
  • progress
  • bare metal
  • gold standard

Cite this

McGinty, S., McCormick, C., McKee, S., Wheel, M., Kennedy, S., & Oldroyd, K. G. (2013). Simulating drug-eluting stents: progress made and the way forward. 664-671. Paper presented at Special Session on Modelling and Simulation in Biology and Medicine (BIOMED 2013), Reykajvik, Iceland.
McGinty, Sean ; McCormick, Christopher ; McKee, Sean ; Wheel, Marcus ; Kennedy, Simon ; Oldroyd, Keith G. / Simulating drug-eluting stents : progress made and the way forward. Paper presented at Special Session on Modelling and Simulation in Biology and Medicine (BIOMED 2013), Reykajvik, Iceland.8 p.
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abstract = "Drug-eluting stents have significantly improved the treatment of coronary artery disease. Compared with their bare metal predecessors, they offer reduced rates of restenosis and thus represent the current gold standard in percutaneous coronary interventions. Drug-eluting stents have been around for over a decade, and while progress is continually being made, they are not suitable in all patients and lesion types. Furthermore there are still real concerns over incomplete healing and late stent thrombosis. In this paper, some modelling approaches are reviewed and the future of modelling and simulation in this field is discussed.",
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note = "Special Session on Modelling and Simulation in Biology and Medicine (BIOMED 2013) ; Conference date: 29-07-2013 Through 31-07-2013",

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McGinty, S, McCormick, C, McKee, S, Wheel, M, Kennedy, S & Oldroyd, KG 2013, 'Simulating drug-eluting stents: progress made and the way forward' Paper presented at Special Session on Modelling and Simulation in Biology and Medicine (BIOMED 2013), Reykajvik, Iceland, 29/07/13 - 31/07/13, pp. 664-671.

Simulating drug-eluting stents : progress made and the way forward. / McGinty, Sean; McCormick, Christopher; McKee, Sean; Wheel, Marcus; Kennedy, Simon; Oldroyd, Keith G.

2013. 664-671 Paper presented at Special Session on Modelling and Simulation in Biology and Medicine (BIOMED 2013), Reykajvik, Iceland.

Research output: Contribution to conferencePaper

TY - CONF

T1 - Simulating drug-eluting stents

T2 - progress made and the way forward

AU - McGinty, Sean

AU - McCormick, Christopher

AU - McKee, Sean

AU - Wheel, Marcus

AU - Kennedy, Simon

AU - Oldroyd, Keith G.

PY - 2013/7

Y1 - 2013/7

N2 - Drug-eluting stents have significantly improved the treatment of coronary artery disease. Compared with their bare metal predecessors, they offer reduced rates of restenosis and thus represent the current gold standard in percutaneous coronary interventions. Drug-eluting stents have been around for over a decade, and while progress is continually being made, they are not suitable in all patients and lesion types. Furthermore there are still real concerns over incomplete healing and late stent thrombosis. In this paper, some modelling approaches are reviewed and the future of modelling and simulation in this field is discussed.

AB - Drug-eluting stents have significantly improved the treatment of coronary artery disease. Compared with their bare metal predecessors, they offer reduced rates of restenosis and thus represent the current gold standard in percutaneous coronary interventions. Drug-eluting stents have been around for over a decade, and while progress is continually being made, they are not suitable in all patients and lesion types. Furthermore there are still real concerns over incomplete healing and late stent thrombosis. In this paper, some modelling approaches are reviewed and the future of modelling and simulation in this field is discussed.

KW - drug-eluting stents

KW - coronary artery disease

KW - progress

KW - bare metal

KW - gold standard

UR - http://www.simultech.org/?y=2013

UR - http://www.scitepress.org/DigitalLibrary/Link.aspx?doi=10.5220/0004622706640672

M3 - Paper

SP - 664

EP - 671

ER -

McGinty S, McCormick C, McKee S, Wheel M, Kennedy S, Oldroyd KG. Simulating drug-eluting stents: progress made and the way forward. 2013. Paper presented at Special Session on Modelling and Simulation in Biology and Medicine (BIOMED 2013), Reykajvik, Iceland.