TY - JOUR

T1 - Simple model for tuberculosis in cattle and badgers

AU - Cox, D.R.

AU - Donnelly, C.A.

AU - Bourne, F.J.

AU - Gettinby, G.

AU - McInerney, J.P.

AU - Morrison, W.I.

AU - Woodroffe, R.

PY - 2005/12/6

Y1 - 2005/12/6

N2 - As an aid to the study of bovine tuberculosis (TB), a simple model has been developed of an epidemic involving two species, cattle and badgers. Each species may infect the other. The proportion of animals affected is assumed relatively small so that the usual nonlinear aspects of epidemic theory are avoided. The model is used to study the long-run and transient effect on cattle of culling badgers and the effect of a period without routine testing for TB, such as occurred during the 2001 epidemic of foot-and-mouth disease in Great Britain. Finally, by examining the changes in cattle TB over the last 15 years, and with some other working assumptions, it is estimated that the net reproduction number of the epidemic is ≈1.1. The implications for controlling the disease are discussed.

AB - As an aid to the study of bovine tuberculosis (TB), a simple model has been developed of an epidemic involving two species, cattle and badgers. Each species may infect the other. The proportion of animals affected is assumed relatively small so that the usual nonlinear aspects of epidemic theory are avoided. The model is used to study the long-run and transient effect on cattle of culling badgers and the effect of a period without routine testing for TB, such as occurred during the 2001 epidemic of foot-and-mouth disease in Great Britain. Finally, by examining the changes in cattle TB over the last 15 years, and with some other working assumptions, it is estimated that the net reproduction number of the epidemic is ≈1.1. The implications for controlling the disease are discussed.

KW - animal ecology

KW - epidemiology

KW - mathematical model

UR - http://dx.doi.org/10.1073/pnas.0509003102

U2 - 10.1073/pnas.0509003102

DO - 10.1073/pnas.0509003102

M3 - Article

VL - 102

SP - 17588

EP - 17593

JO - Proceedings of the National Academy of Sciences

JF - Proceedings of the National Academy of Sciences

SN - 1091-6490

IS - 49

ER -