Silk hydrogels for drug and cell delivery

F. Philipp Seib

Silk hydrogels for drug and cell delivery

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Abstract

Silk has fascinated humans since ancient times; silk fibres have been used in textiles for more than 5,000 years and for many centuries as a suturing material (Lubec, Holbaubek et al. 1993, Omenetto and Kaplan 2010). The remarkable strength and toughness of silk stems from its evolution as a structural engineering material in nature (Vollrath and Porter 2009, Buehler 2013). Silk is a sustainable and ecologically benign biopolymer that can be manufactured using
green processes (Vollrath and Porter 2009). Over the past 25 years, we have seen a tremendous development of both bottom-up and top-down approaches for the generation of silk biopolymers.

Original language	English
Title of host publication	Hydrogels
Subtitle of host publication	Design, Synthesis & Application in Drug Delivery & Regenerative Medicine
Editors	Thakur Raghu Raj Singh, Garry Laverty, Ryan Donnelly
Pages	208-227
Number of pages	20
Publication status	Published - 12 Aug 2017

Keywords

silk hydrogels
drug delivery
gelation
biopharmaceuticals
drug release
stem cell delivery

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Seib-CRC-2017-Silk-hydrogels-for-drug-and-cellAccepted author manuscript, 1.68 MB

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title = "Silk hydrogels for drug and cell delivery",

abstract = "Silk has fascinated humans since ancient times; silk fibres have been used in textiles for more than 5,000 years and for many centuries as a suturing material (Lubec, Holbaubek et al. 1993, Omenetto and Kaplan 2010). The remarkable strength and toughness of silk stems from its evolution as a structural engineering material in nature (Vollrath and Porter 2009, Buehler 2013). Silk is a sustainable and ecologically benign biopolymer that can be manufactured usinggreen processes (Vollrath and Porter 2009). Over the past 25 years, we have seen a tremendous development of both bottom-up and top-down approaches for the generation of silk biopolymers.",

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N2 - Silk has fascinated humans since ancient times; silk fibres have been used in textiles for more than 5,000 years and for many centuries as a suturing material (Lubec, Holbaubek et al. 1993, Omenetto and Kaplan 2010). The remarkable strength and toughness of silk stems from its evolution as a structural engineering material in nature (Vollrath and Porter 2009, Buehler 2013). Silk is a sustainable and ecologically benign biopolymer that can be manufactured usinggreen processes (Vollrath and Porter 2009). Over the past 25 years, we have seen a tremendous development of both bottom-up and top-down approaches for the generation of silk biopolymers.

AB - Silk has fascinated humans since ancient times; silk fibres have been used in textiles for more than 5,000 years and for many centuries as a suturing material (Lubec, Holbaubek et al. 1993, Omenetto and Kaplan 2010). The remarkable strength and toughness of silk stems from its evolution as a structural engineering material in nature (Vollrath and Porter 2009, Buehler 2013). Silk is a sustainable and ecologically benign biopolymer that can be manufactured usinggreen processes (Vollrath and Porter 2009). Over the past 25 years, we have seen a tremendous development of both bottom-up and top-down approaches for the generation of silk biopolymers.

KW - silk hydrogels

KW - drug delivery

KW - gelation

KW - biopharmaceuticals

KW - drug release

KW - stem cell delivery

UR - https://www.crcpress.com/Hydrogels-Design-Synthesis-and-Application-in-Drug-Delivery--Regenerative/Singh-Laverty-Donnelly/p/book/9781498748612

M3 - Chapter

SN - 9781498748612

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BT - Hydrogels

A2 - Singh, Thakur Raghu Raj

A2 - Laverty, Garry

A2 - Donnelly, Ryan

ER -

Silk hydrogels for drug and cell delivery

Abstract

Keywords

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Engineering self-assembling silk hydrogels for the delivery of stem cells

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Silk hydrogels for drug and cell delivery

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Keywords

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Engineering self-assembling silk hydrogels for the delivery of stem cells

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