Silk for drug delivery applications: opportunities and challenges

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Abstract

Silk fibers have been used in textiles for more than 5,000 years and as a suturing material for many centuries. The recent development of new applications for silks include drug delivery. An overview of this new field is provided, summarizing the development of emerging drug delivery applications which include silk-based nanomedicines and transdermal delivery systems We also highlight some of the challenges in developing silk-based drug delivery systems.
Original languageEnglish
Pages (from-to)756-766
Number of pages11
JournalIsrael Journal of Chemistry
Volume53
Issue number9-10
DOIs
Publication statusPublished - Oct 2013

Keywords

  • nanostructures
  • silk
  • biomaterials
  • drug delivery
  • fibrous proteins

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    Littlejohn, D., Anaya-Lara, O., Ault, G., Bennet, D. J., Birch, D., Booth, C., Burt, G., Chen, Y., Chen, H., Fedorov, M., Finney, S., Fletcher, A., Gu, E., Guilhabert, B. J. E., Hastie, J., Jaroszynski, D., Johnston, A., Judd, M., Kockar, I., Lamprou, D., Laurand, N., Macdonald, M., Massoubre, D., Mathieson, K., McKnight, L., Nordon, A., Norman, P., Oliveira, M., Papoff, F., Patwardhan, S., Portugues, I., Scanlon, T., Sefcik, J., Seib, P., Skabara, P., Stack, M., Stephen, B., Tuttle, T., Ulijn, R., Xiao, Q., Yan, X., Zagnoni, M., Dawson, M., Florence, A., Graham, D., McArthur, S., Reese, J., Zhang, Y., Ivanistsev, V., Jawor-Baczynska, A. M., Jones, C., McGlone, T. & McKendry, J.

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