Short-Term Memory Binding and Semantic Network Strength Reinforce Prospective Memory in Older Adults

Mollie Paster, Mario Parra Rodriguez, David P. Salmon, Diane M. Jacobs

Research output: Contribution to conferencePoster

Abstract

Objective Prospective memory (Pro-M), or remembering to carry out a future task, is critical to everyday functioning, but is not assessed by traditional neuropsychological measures. In this study, we investigated neurocognitive mechanisms underlying Pro-M ability in older adults. Participants and Methods 48 nondemented older adults (M age=75.2; SD=2.1) were recruited from the UCSD Alzheimer’s Disease Research Center (ADRC). Participants were 60% female and averaged 17.2 years (SD=2.1) of education. The Memory for Intentions Screening Test (MIST; Raskin et al., 2010) and a visual short-term memory (STM) binding task (Parra et al., 2017) were administered in a single session. Results were compared with scores on traditional neuropsychological measures from a recent ADRC annual assessment. Results Overall performance on the MIST was significantly correlated with shape-color binding accuracy (r=0.38; p<0.05) and Animal Fluency (r=0.29; p<0.05), but was not associated with traditional tests of episodic memory (e.g., CVLT, Logical Memory) or executive functioning (e.g., WCST, Trails B) (all p values > 0.10). Analysis of errors on MIST time-cued tasks revealed the most common error was performing an incorrect task at the prescribed time (61%), whereas performing the prescribed task at the incorrect time was relatively infrequent (13%). Conclusions Performance of non-demented older adults on Pro-M was associated with STM binding and category fluency but not episodic memory or executive functioning. These results suggest that Pro-M is a unique aspect of memory functioning that is distinct from episodic memory and requires synthesizing multiple cognitive strategies. Participants with a stronger semantic network may be able to create a strong association for the intention at the time of encoding, while Pro-M failures could be explained by a failure to adequately bind the semantic components of the encoded intention and the future action.

Conference

ConferenceInternational Neuropsychological Society 47th Annual Meeting
CountryUnited States
CityNew York
Period20/02/1923/02/19

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Episodic Memory
Short-Term Memory
Semantics
Alzheimer Disease
Aptitude
Research
Color
Education

Cite this

Paster, M., Parra Rodriguez, M., Salmon, D. P., & Jacobs , D. M. (Accepted/In press). Short-Term Memory Binding and Semantic Network Strength Reinforce Prospective Memory in Older Adults. Poster session presented at International Neuropsychological Society 47th Annual Meeting, New York, United States.
Paster, Mollie ; Parra Rodriguez, Mario ; Salmon, David P. ; Jacobs , Diane M. . / Short-Term Memory Binding and Semantic Network Strength Reinforce Prospective Memory in Older Adults. Poster session presented at International Neuropsychological Society 47th Annual Meeting, New York, United States.
@conference{653f94a8a60b4b5ba05feb639152603a,
title = "Short-Term Memory Binding and Semantic Network Strength Reinforce Prospective Memory in Older Adults",
abstract = "Objective Prospective memory (Pro-M), or remembering to carry out a future task, is critical to everyday functioning, but is not assessed by traditional neuropsychological measures. In this study, we investigated neurocognitive mechanisms underlying Pro-M ability in older adults. Participants and Methods 48 nondemented older adults (M age=75.2; SD=2.1) were recruited from the UCSD Alzheimer’s Disease Research Center (ADRC). Participants were 60{\%} female and averaged 17.2 years (SD=2.1) of education. The Memory for Intentions Screening Test (MIST; Raskin et al., 2010) and a visual short-term memory (STM) binding task (Parra et al., 2017) were administered in a single session. Results were compared with scores on traditional neuropsychological measures from a recent ADRC annual assessment. Results Overall performance on the MIST was significantly correlated with shape-color binding accuracy (r=0.38; p<0.05) and Animal Fluency (r=0.29; p<0.05), but was not associated with traditional tests of episodic memory (e.g., CVLT, Logical Memory) or executive functioning (e.g., WCST, Trails B) (all p values > 0.10). Analysis of errors on MIST time-cued tasks revealed the most common error was performing an incorrect task at the prescribed time (61{\%}), whereas performing the prescribed task at the incorrect time was relatively infrequent (13{\%}). Conclusions Performance of non-demented older adults on Pro-M was associated with STM binding and category fluency but not episodic memory or executive functioning. These results suggest that Pro-M is a unique aspect of memory functioning that is distinct from episodic memory and requires synthesizing multiple cognitive strategies. Participants with a stronger semantic network may be able to create a strong association for the intention at the time of encoding, while Pro-M failures could be explained by a failure to adequately bind the semantic components of the encoded intention and the future action.",
author = "Mollie Paster and {Parra Rodriguez}, Mario and Salmon, {David P.} and Jacobs, {Diane M.}",
year = "2018",
month = "10",
day = "1",
language = "English",
note = "International Neuropsychological Society 47th Annual Meeting : Embracing the Biopsychosocial Melting Pot ; Conference date: 20-02-2019 Through 23-02-2019",

}

Paster, M, Parra Rodriguez, M, Salmon, DP & Jacobs , DM 2018, 'Short-Term Memory Binding and Semantic Network Strength Reinforce Prospective Memory in Older Adults' International Neuropsychological Society 47th Annual Meeting, New York, United States, 20/02/19 - 23/02/19, .

Short-Term Memory Binding and Semantic Network Strength Reinforce Prospective Memory in Older Adults. / Paster, Mollie ; Parra Rodriguez, Mario; Salmon, David P. ; Jacobs , Diane M. .

2018. Poster session presented at International Neuropsychological Society 47th Annual Meeting, New York, United States.

Research output: Contribution to conferencePoster

TY - CONF

T1 - Short-Term Memory Binding and Semantic Network Strength Reinforce Prospective Memory in Older Adults

AU - Paster, Mollie

AU - Parra Rodriguez, Mario

AU - Salmon, David P.

AU - Jacobs , Diane M.

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Objective Prospective memory (Pro-M), or remembering to carry out a future task, is critical to everyday functioning, but is not assessed by traditional neuropsychological measures. In this study, we investigated neurocognitive mechanisms underlying Pro-M ability in older adults. Participants and Methods 48 nondemented older adults (M age=75.2; SD=2.1) were recruited from the UCSD Alzheimer’s Disease Research Center (ADRC). Participants were 60% female and averaged 17.2 years (SD=2.1) of education. The Memory for Intentions Screening Test (MIST; Raskin et al., 2010) and a visual short-term memory (STM) binding task (Parra et al., 2017) were administered in a single session. Results were compared with scores on traditional neuropsychological measures from a recent ADRC annual assessment. Results Overall performance on the MIST was significantly correlated with shape-color binding accuracy (r=0.38; p<0.05) and Animal Fluency (r=0.29; p<0.05), but was not associated with traditional tests of episodic memory (e.g., CVLT, Logical Memory) or executive functioning (e.g., WCST, Trails B) (all p values > 0.10). Analysis of errors on MIST time-cued tasks revealed the most common error was performing an incorrect task at the prescribed time (61%), whereas performing the prescribed task at the incorrect time was relatively infrequent (13%). Conclusions Performance of non-demented older adults on Pro-M was associated with STM binding and category fluency but not episodic memory or executive functioning. These results suggest that Pro-M is a unique aspect of memory functioning that is distinct from episodic memory and requires synthesizing multiple cognitive strategies. Participants with a stronger semantic network may be able to create a strong association for the intention at the time of encoding, while Pro-M failures could be explained by a failure to adequately bind the semantic components of the encoded intention and the future action.

AB - Objective Prospective memory (Pro-M), or remembering to carry out a future task, is critical to everyday functioning, but is not assessed by traditional neuropsychological measures. In this study, we investigated neurocognitive mechanisms underlying Pro-M ability in older adults. Participants and Methods 48 nondemented older adults (M age=75.2; SD=2.1) were recruited from the UCSD Alzheimer’s Disease Research Center (ADRC). Participants were 60% female and averaged 17.2 years (SD=2.1) of education. The Memory for Intentions Screening Test (MIST; Raskin et al., 2010) and a visual short-term memory (STM) binding task (Parra et al., 2017) were administered in a single session. Results were compared with scores on traditional neuropsychological measures from a recent ADRC annual assessment. Results Overall performance on the MIST was significantly correlated with shape-color binding accuracy (r=0.38; p<0.05) and Animal Fluency (r=0.29; p<0.05), but was not associated with traditional tests of episodic memory (e.g., CVLT, Logical Memory) or executive functioning (e.g., WCST, Trails B) (all p values > 0.10). Analysis of errors on MIST time-cued tasks revealed the most common error was performing an incorrect task at the prescribed time (61%), whereas performing the prescribed task at the incorrect time was relatively infrequent (13%). Conclusions Performance of non-demented older adults on Pro-M was associated with STM binding and category fluency but not episodic memory or executive functioning. These results suggest that Pro-M is a unique aspect of memory functioning that is distinct from episodic memory and requires synthesizing multiple cognitive strategies. Participants with a stronger semantic network may be able to create a strong association for the intention at the time of encoding, while Pro-M failures could be explained by a failure to adequately bind the semantic components of the encoded intention and the future action.

M3 - Poster

ER -

Paster M, Parra Rodriguez M, Salmon DP, Jacobs DM. Short-Term Memory Binding and Semantic Network Strength Reinforce Prospective Memory in Older Adults. 2018. Poster session presented at International Neuropsychological Society 47th Annual Meeting, New York, United States.