Sex hormones and modulation of immunity against leishmaniasis

Heidi Snider, Claudio Lezama-Davila, J. Alexander, Abhay R. Satoskar

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Sex-associated hormones such as estradiol, testosterone and progesterone have all been shown to modulate immune responses, which can result in differential disease outcomes between males and females, as well as between pregnant and nonpregnant females. Most parasitic diseases, including leishmaniasis, usually result in more severe disease in males compared with females. This review highlights our current knowledge concerning the role of sex hormones in modulating leishmaniasis in both clinical settings and experimental disease models.
Original languageEnglish
Pages (from-to)106-113
Number of pages7
JournalNeuroimmunomodulation
Volume16
Issue number2
DOIs
Publication statusPublished - 2009

Fingerprint

Leishmaniasis
Gonadal Steroid Hormones
Immunity
Parasitic Diseases
Progesterone
Testosterone
Estradiol
Theoretical Models

Keywords

  • leishmaniasis
  • sex-associated hormones
  • immune responses
  • biomedical sciences
  • pharmacology

Cite this

Snider, Heidi ; Lezama-Davila, Claudio ; Alexander, J. ; Satoskar, Abhay R. / Sex hormones and modulation of immunity against leishmaniasis. In: Neuroimmunomodulation. 2009 ; Vol. 16, No. 2. pp. 106-113.
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Sex hormones and modulation of immunity against leishmaniasis. / Snider, Heidi; Lezama-Davila, Claudio; Alexander, J.; Satoskar, Abhay R.

In: Neuroimmunomodulation, Vol. 16, No. 2, 2009, p. 106-113.

Research output: Contribution to journalArticle

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