SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence

K. Faulds, R.P. Barbagallo, J.T. Keer, W.E. Smith, D. Graham

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

This communication contains data from a comparison between the detection limits obtained using surface enhanced resonance Raman scattering (SERRS) and fluorescence detection of dye labelled oligonucleotides. The results show that the detection limits for SERRS are generally at least three orders of magnitude lower than those obtained for fluorescence.
LanguageEnglish
Pages567-568
Number of pages1
JournalAnalyst
Volume129
Issue number7
DOIs
Publication statusPublished - 2004

Fingerprint

Raman Spectrum Analysis
Oligonucleotides
Limit of Detection
Raman scattering
fluorescence
Fluorescence
scattering
Coloring Agents
Dyes
Communication
dye
communication
detection

Keywords

  • surface-enhanced raman
  • silver
  • scattering
  • spectroscopy
  • molecules
  • dyes

Cite this

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abstract = "This communication contains data from a comparison between the detection limits obtained using surface enhanced resonance Raman scattering (SERRS) and fluorescence detection of dye labelled oligonucleotides. The results show that the detection limits for SERRS are generally at least three orders of magnitude lower than those obtained for fluorescence.",
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SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence. / Faulds, K.; Barbagallo, R.P.; Keer, J.T.; Smith, W.E.; Graham, D.

In: Analyst, Vol. 129, No. 7, 2004, p. 567-568.

Research output: Contribution to journalArticle

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AU - Keer, J.T.

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AU - Graham, D.

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AB - This communication contains data from a comparison between the detection limits obtained using surface enhanced resonance Raman scattering (SERRS) and fluorescence detection of dye labelled oligonucleotides. The results show that the detection limits for SERRS are generally at least three orders of magnitude lower than those obtained for fluorescence.

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KW - silver

KW - scattering

KW - spectroscopy

KW - molecules

KW - dyes

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