Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

King Hang Aaron Lau, Valeria Castelletto, Thomas Kendall, Jan Sefcik, Ian W. Hamley, Mehedi Reza, Janne Ruokolainen

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small pep- tidomimetic nanospheres.
LanguageEnglish
Pages2178-2181
Number of pages4
JournalChemical Communications
Volume53
Issue number13
Early online date25 Jan 2017
DOIs
Publication statusPublished - 9 Feb 2017

Fingerprint

Peptoids
Micelles
Self assembly
N-substituted Glycines
Nanospheres
Peptides
Amino acids
Nanostructures

Keywords

  • amphiphilic lipopeptoids
  • peptoids
  • peptoid nanostructures
  • peptidomimetic nanospheres

Cite this

Lau, K. H. A., Castelletto, V., Kendall, T., Sefcik, J., Hamley, I. W., Reza, M., & Ruokolainen, J. (2017). Self-assembly of ultra-small micelles from amphiphilic lipopeptoids. Chemical Communications, 53(13), 2178-2181. https://doi.org/10.1039/C6CC09888F
Lau, King Hang Aaron ; Castelletto, Valeria ; Kendall, Thomas ; Sefcik, Jan ; Hamley, Ian W. ; Reza, Mehedi ; Ruokolainen, Janne. / Self-assembly of ultra-small micelles from amphiphilic lipopeptoids. In: Chemical Communications. 2017 ; Vol. 53, No. 13. pp. 2178-2181.
@article{bba0da461ef34fb9aea27510df2cda02,
title = "Self-assembly of ultra-small micelles from amphiphilic lipopeptoids",
abstract = "Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small pep- tidomimetic nanospheres.",
keywords = "amphiphilic lipopeptoids, peptoids, peptoid nanostructures, peptidomimetic nanospheres",
author = "Lau, {King Hang Aaron} and Valeria Castelletto and Thomas Kendall and Jan Sefcik and Hamley, {Ian W.} and Mehedi Reza and Janne Ruokolainen",
year = "2017",
month = "2",
day = "9",
doi = "10.1039/C6CC09888F",
language = "English",
volume = "53",
pages = "2178--2181",
journal = "Chemical Communications",
issn = "1359-7345",
number = "13",

}

Lau, KHA, Castelletto, V, Kendall, T, Sefcik, J, Hamley, IW, Reza, M & Ruokolainen, J 2017, 'Self-assembly of ultra-small micelles from amphiphilic lipopeptoids' Chemical Communications, vol. 53, no. 13, pp. 2178-2181. https://doi.org/10.1039/C6CC09888F

Self-assembly of ultra-small micelles from amphiphilic lipopeptoids. / Lau, King Hang Aaron; Castelletto, Valeria; Kendall, Thomas; Sefcik, Jan; Hamley, Ian W.; Reza, Mehedi; Ruokolainen, Janne.

In: Chemical Communications, Vol. 53, No. 13, 09.02.2017, p. 2178-2181.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

AU - Lau, King Hang Aaron

AU - Castelletto, Valeria

AU - Kendall, Thomas

AU - Sefcik, Jan

AU - Hamley, Ian W.

AU - Reza, Mehedi

AU - Ruokolainen, Janne

PY - 2017/2/9

Y1 - 2017/2/9

N2 - Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small pep- tidomimetic nanospheres.

AB - Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small pep- tidomimetic nanospheres.

KW - amphiphilic lipopeptoids

KW - peptoids

KW - peptoid nanostructures

KW - peptidomimetic nanospheres

U2 - 10.1039/C6CC09888F

DO - 10.1039/C6CC09888F

M3 - Article

VL - 53

SP - 2178

EP - 2181

JO - Chemical Communications

T2 - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 13

ER -