Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small pep- tidomimetic nanospheres.
- amphiphilic lipopeptoids
- peptoid nanostructures
- peptidomimetic nanospheres
Lau, K. H. A., Castelletto, V., Kendall, T., Sefcik, J., Hamley, I. W., Reza, M., & Ruokolainen, J. (2017). Self-assembly of ultra-small micelles from amphiphilic lipopeptoids. Chemical Communications, 53(13), 2178-2181. https://doi.org/10.1039/C6CC09888F