Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

D. McKeown, C.J. McHugh, A. McCabe, W.E. Smith, D. Graham

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.
LanguageEnglish
Pages1227-1230
Number of pages3
JournalHeterocycles
Volume57
Issue number7
Publication statusPublished - 1 Jul 2002

Fingerprint

Triazoles
Amines
Nucleophiles
Metals
Molecules

Keywords

  • benzotriazole
  • chemistry
  • organic

Cite this

McKeown, D. ; McHugh, C.J. ; McCabe, A. ; Smith, W.E. ; Graham, D. / Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine. In: Heterocycles. 2002 ; Vol. 57, No. 7. pp. 1227-1230.
@article{e9e67c981b494dc0bdc7c5217c3d9f23,
title = "Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine",
abstract = "The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.",
keywords = "benzotriazole, chemistry, organic",
author = "D. McKeown and C.J. McHugh and A. McCabe and W.E. Smith and D. Graham",
year = "2002",
month = "7",
day = "1",
language = "English",
volume = "57",
pages = "1227--1230",
journal = "Heterocycles",
issn = "0385-5414",
number = "7",

}

Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine. / McKeown, D.; McHugh, C.J.; McCabe, A.; Smith, W.E.; Graham, D.

In: Heterocycles, Vol. 57, No. 7, 01.07.2002, p. 1227-1230.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Selective protection of 5-aminobenzotriazole for controlled reaction at the primary amine

AU - McKeown, D.

AU - McHugh, C.J.

AU - McCabe, A.

AU - Smith, W.E.

AU - Graham, D.

PY - 2002/7/1

Y1 - 2002/7/1

N2 - The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.

AB - The selective protection of the triazole function of 5-aminobenzotriazole is reported. Two different protecting groups were used to prevent side reactions through the triazole amine acting as a leaving group when 5-aminobenzotriazole was used as a nucleophile. This allowed the addition of aminobenzotriazole to two target molecules to impart metal complexing properties to the new species.

KW - benzotriazole

KW - chemistry

KW - organic

M3 - Article

VL - 57

SP - 1227

EP - 1230

JO - Heterocycles

T2 - Heterocycles

JF - Heterocycles

SN - 0385-5414

IS - 7

ER -