Selective enrichment of anti-inflammatory drugs from river water samples by solid-phase extraction with a molecularly imprinted polymer

E. Caro, R.M. Marce, P.A.G. Cormack, D.C. Sherrington, F. Borrull

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

A molecularly imprinted polymer (MIP) is synthesised by a noncovalent protocol in which ibuprofen was used as a template molecule. The polymer was evaluated chromatographically and it was seen that the MIP showed cross-reactivity. Subsequently, when this polymer was used as sorbent in SPE it was possible to selectively extract a mixture of nonsteroidal anti-inflammatory drugs from aqueous samples when a cleanup step with dichloromethane was performed. The performance of the MIP was evaluated with river water and water from a wastewater treatment plant, and compared with the performance of a commercial Isolute ENV+ sorbent.
Original languageEnglish
Pages (from-to)2080-2085
Number of pages5
JournalJournal of Separation Science
Volume28
Issue number16
DOIs
Publication statusPublished - Nov 2005

Keywords

  • molecularly imprinted polymer
  • solid-phase extraction
  • ibuprofen
  • river water
  • cross-reactivity

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