Selective enrichment of anti-inflammatory drugs from river water samples by solid-phase extraction with a molecularly imprinted polymer

E. Caro; R.M. Marce; P.A.G. Cormack; D.C. Sherrington; F. Borrull

doi:10.1002/jssc.200500027

Selective enrichment of anti-inflammatory drugs from river water samples by solid-phase extraction with a molecularly imprinted polymer

E. Caro, R.M. Marce, P.A.G. Cormack, D.C. Sherrington, F. Borrull

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

A molecularly imprinted polymer (MIP) is synthesised by a noncovalent protocol in which ibuprofen was used as a template molecule. The polymer was evaluated chromatographically and it was seen that the MIP showed cross-reactivity. Subsequently, when this polymer was used as sorbent in SPE it was possible to selectively extract a mixture of nonsteroidal anti-inflammatory drugs from aqueous samples when a cleanup step with dichloromethane was performed. The performance of the MIP was evaluated with river water and water from a wastewater treatment plant, and compared with the performance of a commercial Isolute ENV+ sorbent.

Original language	English
Pages (from-to)	2080-2085
Number of pages	5
Journal	Journal of Separation Science
Volume	28
Issue number	16
DOIs	https://doi.org/10.1002/jssc.200500027
Publication status	Published - Nov 2005

Keywords

molecularly imprinted polymer
solid-phase extraction
ibuprofen
river water
cross-reactivity

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10.1002/jssc.200500027

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title = "Selective enrichment of anti-inflammatory drugs from river water samples by solid-phase extraction with a molecularly imprinted polymer",

abstract = "A molecularly imprinted polymer (MIP) is synthesised by a noncovalent protocol in which ibuprofen was used as a template molecule. The polymer was evaluated chromatographically and it was seen that the MIP showed cross-reactivity. Subsequently, when this polymer was used as sorbent in SPE it was possible to selectively extract a mixture of nonsteroidal anti-inflammatory drugs from aqueous samples when a cleanup step with dichloromethane was performed. The performance of the MIP was evaluated with river water and water from a wastewater treatment plant, and compared with the performance of a commercial Isolute ENV+ sorbent.",

keywords = "molecularly imprinted polymer, solid-phase extraction, ibuprofen, river water, cross-reactivity",

author = "E. Caro and R.M. Marce and P.A.G. Cormack and D.C. Sherrington and F. Borrull",

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AU - Caro, E.

AU - Marce, R.M.

AU - Cormack, P.A.G.

AU - Sherrington, D.C.

AU - Borrull, F.

PY - 2005/11

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AB - A molecularly imprinted polymer (MIP) is synthesised by a noncovalent protocol in which ibuprofen was used as a template molecule. The polymer was evaluated chromatographically and it was seen that the MIP showed cross-reactivity. Subsequently, when this polymer was used as sorbent in SPE it was possible to selectively extract a mixture of nonsteroidal anti-inflammatory drugs from aqueous samples when a cleanup step with dichloromethane was performed. The performance of the MIP was evaluated with river water and water from a wastewater treatment plant, and compared with the performance of a commercial Isolute ENV+ sorbent.

KW - molecularly imprinted polymer

KW - solid-phase extraction

KW - ibuprofen

KW - river water

KW - cross-reactivity

UR - http://dx.doi.org/10.1002/jssc.200500027

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DO - 10.1002/jssc.200500027

M3 - Article

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SP - 2080

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JO - Journal of Separation Science

JF - Journal of Separation Science

IS - 16

ER -

Selective enrichment of anti-inflammatory drugs from river water samples by solid-phase extraction with a molecularly imprinted polymer

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Keywords

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