Selective bi-specific engagement: assessing monovalent vs bivalent binding

Rachel Duxbury; Rebecca Beveridge; Craig Jamieson; David Jones; Gavin Jones; Zahra Rattray

Selective bi-specific engagement: assessing monovalent vs bivalent binding

Rachel Duxbury, Rebecca Beveridge, Craig Jamieson (Editor), David Jones, Gavin Jones, Zahra Rattray

Research output: Contribution to conference › Poster

Original language	English
Publication status	Published - 21 Nov 2023
Event	JPAG Pharmaceutical Analysis Research Awards and Careers Symposium 2023 - London Duration: 21 Nov 2023 → 21 Nov 2023

Conference

Conference	JPAG Pharmaceutical Analysis Research Awards and Careers Symposium 2023
Abbreviated title	JPAG Research Awards and Careers Symposium 2023
City	London
Period	21/11/23 → 21/11/23

Keywords

Antibody
Bispecific

Cite this

@conference{d866d94fc43e445f844c36a6233271d5,

title = "Selective bi-specific engagement: assessing monovalent vs bivalent binding",

keywords = "Antibody, Bispecific",

author = "Rachel Duxbury and Rebecca Beveridge and Craig Jamieson and David Jones and Gavin Jones and Zahra Rattray",

year = "2023",

month = nov,

day = "21",

language = "English",

note = "JPAG Pharmaceutical Analysis Research Awards and Careers Symposium 2023, JPAG Research Awards and Careers Symposium 2023 ; Conference date: 21-11-2023 Through 21-11-2023",

}

TY - CONF

T1 - Selective bi-specific engagement

T2 - JPAG Pharmaceutical Analysis Research Awards and Careers Symposium 2023

AU - Duxbury, Rachel

AU - Beveridge, Rebecca

AU - Jones, David

AU - Jones, Gavin

AU - Rattray, Zahra

A2 - Jamieson, Craig

PY - 2023/11/21

Y1 - 2023/11/21

KW - Antibody

KW - Bispecific

UR - https://www.rsc.org/events/detail/77488/jpag-pharmaceutical-analysis-research-awards-and-careers-symposium-2023

M3 - Poster

Y2 - 21 November 2023 through 21 November 2023

ER -

Selective bi-specific engagement: assessing monovalent vs bivalent binding

Conference

Keywords

Other files and links

Understanding the relationship between target affinities of bi-specific antibodies to dual cell-membrane targets and their impact on cell binding and selectivity to improve the accuracy and value of in silico modelling for prediction of the optimal target affinities for effective clinical outcomes

Cite this

Selective bi-specific engagement: assessing monovalent vs bivalent binding

Conference

Keywords

Other files and links

Projects

Understanding the relationship between target affinities of bi-specific antibodies to dual cell-membrane targets and their impact on cell binding and selectivity to improve the accuracy and value of in silico modelling for prediction of the optimal target affinities for effective clinical outcomes

Cite this