Projects per year
Abstract
Although Grubbs metathesis catalysts have enabled syntheses of a range of molecules, alkene isomerization, a known and problematic side reaction, is poorly understood. Several mechanisms which have been advanced to account for isomerization were studied by using electronic structure calculations. The pathway catalyzed by a ruthenium hydride emerged as the most facile process by a significant margin. For the first time, we have obtained experimental evidence for the presence of this species in a metathesis-active system.
Original language | English |
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Pages (from-to) | 5673–5677 |
Number of pages | 5 |
Journal | European Journal of Organic Chemistry |
Volume | 2012 |
Issue number | 29 |
DOIs | |
Publication status | Published - Oct 2012 |
Keywords
- ruthenium
- metathesis
- homogeneous catalysis
- density functional calculations
- kinetics
Fingerprint Dive into the research topics of 'Searching for the hidden hydrides: the competition between alkene isomerization and metathesis with Grubbs catalysts'. Together they form a unique fingerprint.
Projects
- 2 Finished
-
Quantifying the Interplay of Structure and Reactivity in Ring Closing Metathesis (QuIStRiC)
Percy, J.
EPSRC (Engineering and Physical Sciences Research Council)
1/04/09 → 31/07/12
Project: Research