The inorganic cage compounds, dicarba-closo-dodecaboranes (carboranes), are chemical building blocks of remarkable thermal and chemical stability, with spherical geometry and exceptional hydrophobic character. We have focused on medicinal drug design using carboranes as a hydrophobic pharmacophore and have developed a potent estrogen agonist, BE120. We also have applied carboranes for structural chemistry, utilizing their specific three-dimensional character to obtain multilayer aromatic structures.
|Number of pages||3|
|Journal||Phosphorus, Sulfur, and Silicon and the Related Elements|
|Publication status||Published - Apr 2004|
- inorganic cage compounds
- medicinal pharmacophore
- estrogen agonist
Henderson, K. W., Kennedy, A. R., & MacDougall, D. J. (2004). S-block complexes of a, α'-stabilized carbanions: Rings, chains, and 2D networks. Phosphorus, Sulfur, and Silicon and the Related Elements , 179(4/5), 795-798. https://doi.org/10.1080/10426500490427088