Abstract
A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.
| Original language | English |
|---|---|
| Pages (from-to) | 522-524 |
| Number of pages | 3 |
| Journal | Biochemical Society Transactions |
| Volume | 38 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2010 |
Keywords
- acylation
- acyltransferases
- animals
- catalysis
- humans
- membrane proteins
- multigene family
- proteins
- substrate specificity
- tissue distribution