S-acylation by the DHHC protein family

Jennifer Greaves, Luke H Chamberlain

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.
Original languageEnglish
Pages (from-to)522-524
Number of pages3
JournalBiochemical Society Transactions
Issue number2
Publication statusPublished - 2010


  • acylation
  • acyltransferases
  • animals
  • catalysis
  • humans
  • membrane proteins
  • multigene family
  • proteins
  • substrate specificity
  • tissue distribution


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