S-acylation by the DHHC protein family

Jennifer Greaves, Luke H Chamberlain

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.
LanguageEnglish
Pages522-524
Number of pages3
JournalBiochemical Society Transactions
Volume38
Issue number2
DOIs
Publication statusPublished - 2010

Fingerprint

Acylation
Acyltransferases
Protein S
Substrate Specificity
Proteins
Substrates

Keywords

  • acylation
  • acyltransferases
  • animals
  • catalysis
  • humans
  • membrane proteins
  • multigene family
  • proteins
  • substrate specificity
  • tissue distribution

Cite this

Greaves, Jennifer ; Chamberlain, Luke H. / S-acylation by the DHHC protein family. In: Biochemical Society Transactions. 2010 ; Vol. 38, No. 2. pp. 522-524.
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S-acylation by the DHHC protein family. / Greaves, Jennifer; Chamberlain, Luke H.

In: Biochemical Society Transactions, Vol. 38, No. 2, 2010, p. 522-524.

Research output: Contribution to journalArticle

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AU - Greaves, Jennifer

AU - Chamberlain, Luke H

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KW - acylation

KW - acyltransferases

KW - animals

KW - catalysis

KW - humans

KW - membrane proteins

KW - multigene family

KW - proteins

KW - substrate specificity

KW - tissue distribution

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