We report a photolabile biselectrophilic Ru(ii) complex that can be used for homo- or heterodimerization of cysteine-containing peptides. The resulting dimers can be efficiently disassembled by long-wavelength light. As proof-of-concept, we describe the preparation of homo-and heterodimeric bZIP peptides whose DNA-binding properties can be turned off using visible light.
- ruthenium bipyridyl complexes
- photolabile biselectrophilic Ru(II) complex
- visible light