Role of topical antibiotics in hip surgery. A prospective randomised study

D. Young, S. Kamath, S. Sinha, E. Shaari, A.C. Campbell

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The effectiveness of topical antibiotics has been shown well enough in vitro to justify strong consideration of their use in orthopaedic procedures. We carried out a randomised prospective trial to study the role of topical chloramphenicol ointment application on postoperative wounds following surgeries for hip fractures. One hundred cases with fracture neck of femur were enrolled in the study. They were randomized into two treatment groups: one group had chloramphenicol ointment applied at the surgical site at the end of procedure and 3rd day postoperatively, while the control group did not. The wound was checked on the 3rd, 6th, 12th and 30th days postoperatively, by a tissue viability nurse on the guidelines issued by the Scottish Centre for Infection and Environmental Health (SCIEH). Awareness is needed amongst the general public about the ill effects of smoking. There was reduction in the incidence of wound infection with the use of topical antibiotic ointment. However, this was not statistically significant to recommend its use in routine practice. A larger study should provide useful information on the role of topical antibiotic and its effect on postoperative wound infection.
LanguageEnglish
Pages783-787
Number of pages4
JournalInjury
Volume36
DOIs
Publication statusPublished - 2005

Fingerprint

Ointments
Hip
Prospective Studies
Chloramphenicol
Anti-Bacterial Agents
Orthopedic Procedures
Surgical Wound Infection
Tissue Survival
Femoral Neck Fractures
Environmental Health
Hip Fractures
Wounds and Injuries
Wound Infection
Smoking
Nurses
Guidelines
Control Groups
Incidence
Infection
Therapeutics

Keywords

  • fracture
  • femur
  • infection
  • antibiotics
  • chloramphenicol
  • surgery
  • statistics

Cite this

Young, D. ; Kamath, S. ; Sinha, S. ; Shaari, E. ; Campbell, A.C. / Role of topical antibiotics in hip surgery. A prospective randomised study. In: Injury. 2005 ; Vol. 36. pp. 783-787.
@article{f0e6274b08a74065847259f9765fbb4d,
title = "Role of topical antibiotics in hip surgery. A prospective randomised study",
abstract = "The effectiveness of topical antibiotics has been shown well enough in vitro to justify strong consideration of their use in orthopaedic procedures. We carried out a randomised prospective trial to study the role of topical chloramphenicol ointment application on postoperative wounds following surgeries for hip fractures. One hundred cases with fracture neck of femur were enrolled in the study. They were randomized into two treatment groups: one group had chloramphenicol ointment applied at the surgical site at the end of procedure and 3rd day postoperatively, while the control group did not. The wound was checked on the 3rd, 6th, 12th and 30th days postoperatively, by a tissue viability nurse on the guidelines issued by the Scottish Centre for Infection and Environmental Health (SCIEH). Awareness is needed amongst the general public about the ill effects of smoking. There was reduction in the incidence of wound infection with the use of topical antibiotic ointment. However, this was not statistically significant to recommend its use in routine practice. A larger study should provide useful information on the role of topical antibiotic and its effect on postoperative wound infection.",
keywords = "fracture, femur, infection, antibiotics, chloramphenicol, surgery, statistics",
author = "D. Young and S. Kamath and S. Sinha and E. Shaari and A.C. Campbell",
year = "2005",
doi = "10.1016/j.injury.2005.01.001",
language = "English",
volume = "36",
pages = "783--787",
journal = "Injury",
issn = "0020-1383",

}

Role of topical antibiotics in hip surgery. A prospective randomised study. / Young, D.; Kamath, S.; Sinha, S.; Shaari, E.; Campbell, A.C.

In: Injury, Vol. 36, 2005, p. 783-787.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Role of topical antibiotics in hip surgery. A prospective randomised study

AU - Young, D.

AU - Kamath, S.

AU - Sinha, S.

AU - Shaari, E.

AU - Campbell, A.C.

PY - 2005

Y1 - 2005

N2 - The effectiveness of topical antibiotics has been shown well enough in vitro to justify strong consideration of their use in orthopaedic procedures. We carried out a randomised prospective trial to study the role of topical chloramphenicol ointment application on postoperative wounds following surgeries for hip fractures. One hundred cases with fracture neck of femur were enrolled in the study. They were randomized into two treatment groups: one group had chloramphenicol ointment applied at the surgical site at the end of procedure and 3rd day postoperatively, while the control group did not. The wound was checked on the 3rd, 6th, 12th and 30th days postoperatively, by a tissue viability nurse on the guidelines issued by the Scottish Centre for Infection and Environmental Health (SCIEH). Awareness is needed amongst the general public about the ill effects of smoking. There was reduction in the incidence of wound infection with the use of topical antibiotic ointment. However, this was not statistically significant to recommend its use in routine practice. A larger study should provide useful information on the role of topical antibiotic and its effect on postoperative wound infection.

AB - The effectiveness of topical antibiotics has been shown well enough in vitro to justify strong consideration of their use in orthopaedic procedures. We carried out a randomised prospective trial to study the role of topical chloramphenicol ointment application on postoperative wounds following surgeries for hip fractures. One hundred cases with fracture neck of femur were enrolled in the study. They were randomized into two treatment groups: one group had chloramphenicol ointment applied at the surgical site at the end of procedure and 3rd day postoperatively, while the control group did not. The wound was checked on the 3rd, 6th, 12th and 30th days postoperatively, by a tissue viability nurse on the guidelines issued by the Scottish Centre for Infection and Environmental Health (SCIEH). Awareness is needed amongst the general public about the ill effects of smoking. There was reduction in the incidence of wound infection with the use of topical antibiotic ointment. However, this was not statistically significant to recommend its use in routine practice. A larger study should provide useful information on the role of topical antibiotic and its effect on postoperative wound infection.

KW - fracture

KW - femur

KW - infection

KW - antibiotics

KW - chloramphenicol

KW - surgery

KW - statistics

UR - http://www.stams.strath.ac.uk/publications/system/modules/downloader.php?file=publications/1003.pdf

UR - http://dx.doi.org/10.1016/j.injury.2005.01.001

U2 - 10.1016/j.injury.2005.01.001

DO - 10.1016/j.injury.2005.01.001

M3 - Article

VL - 36

SP - 783

EP - 787

JO - Injury

T2 - Injury

JF - Injury

SN - 0020-1383

ER -