Abstract
We investigated the feasibility of Remote Centre of Motion (RCM) and viscous material extrusion 3D printing. A hypothetical, intra-articular, regenerative medicine-based treatment technique for focal cartilage defects of the knee was used as a potential example of the application of 3D printing in vivo.
The results of this study suggest, that RCM mechanism is feasible with viscous material extrusion 3D printing processes, without a major trade-off in imprint quality.
The achieved printing accuracy at an average dimensional error of 0.06±0.14mm in this new modality of 3D printing is comparable to those described in literature for other types of bioprinting.
Robotic assisted 3D bio-printing demonstrated here is a viable option for focal cartilage defect restoration.
| Original language | English |
|---|---|
| Article number | 3746 |
| Number of pages | 9 |
| Journal | Scientific Reports |
| Volume | 9 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 6 Mar 2019 |
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Keywords
- 3D bioprinting
- cartilage defects
- focal cartilage
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Robotic-assisted 3D bio-printing for repairing bone and cartilage defects through a minimally invasive approach. / Lipskas, Julius; Deep, Kamal; Yao, Wei.
In: Scientific Reports, Vol. 9, No. 1, 3746, 06.03.2019.Research output: Contribution to journal › Article
TY - JOUR
T1 - Robotic-assisted 3D bio-printing for repairing bone and cartilage defects through a minimally invasive approach
AU - Lipskas, Julius
AU - Deep, Kamal
AU - Yao, Wei
PY - 2019/3/6
Y1 - 2019/3/6
N2 - There is an unmet need for new techniques and methods of healing critical size tissue defects, by further reduction of invasiveness in implant, cell and tissue-based surgery. This paper presents the development of a new regenerative medicine that combines 3D bio-printing and robotic-assisted minimally invasive surgery techniques to meet this need.We investigated the feasibility of Remote Centre of Motion (RCM) and viscous material extrusion 3D printing. A hypothetical, intra-articular, regenerative medicine-based treatment technique for focal cartilage defects of the knee was used as a potential example of the application of 3D printing in vivo.The results of this study suggest, that RCM mechanism is feasible with viscous material extrusion 3D printing processes, without a major trade-off in imprint quality.The achieved printing accuracy at an average dimensional error of 0.06±0.14mm in this new modality of 3D printing is comparable to those described in literature for other types of bioprinting.Robotic assisted 3D bio-printing demonstrated here is a viable option for focal cartilage defect restoration.
AB - There is an unmet need for new techniques and methods of healing critical size tissue defects, by further reduction of invasiveness in implant, cell and tissue-based surgery. This paper presents the development of a new regenerative medicine that combines 3D bio-printing and robotic-assisted minimally invasive surgery techniques to meet this need.We investigated the feasibility of Remote Centre of Motion (RCM) and viscous material extrusion 3D printing. A hypothetical, intra-articular, regenerative medicine-based treatment technique for focal cartilage defects of the knee was used as a potential example of the application of 3D printing in vivo.The results of this study suggest, that RCM mechanism is feasible with viscous material extrusion 3D printing processes, without a major trade-off in imprint quality.The achieved printing accuracy at an average dimensional error of 0.06±0.14mm in this new modality of 3D printing is comparable to those described in literature for other types of bioprinting.Robotic assisted 3D bio-printing demonstrated here is a viable option for focal cartilage defect restoration.
KW - 3D bioprinting
KW - cartilage defects
KW - focal cartilage
U2 - 10.1038/s41598-019-38972-2
DO - 10.1038/s41598-019-38972-2
M3 - Article
VL - 9
JO - Scientific Reports
JF - Scientific Reports
SN - 2045-2322
IS - 1
M1 - 3746
ER -