Projects per year
Abstract
There is an unmet need for new techniques and methods of healing critical size tissue defects, by further reduction of invasiveness in implant, cell and tissue-based surgery. This paper presents the development of a new regenerative medicine that combines 3D bio-printing and robotic-assisted minimally invasive surgery techniques to meet this need.
We investigated the feasibility of Remote Centre of Motion (RCM) and viscous material extrusion 3D printing. A hypothetical, intra-articular, regenerative medicine-based treatment technique for focal cartilage defects of the knee was used as a potential example of the application of 3D printing in vivo.
The results of this study suggest, that RCM mechanism is feasible with viscous material extrusion 3D printing processes, without a major trade-off in imprint quality.
The achieved printing accuracy at an average dimensional error of 0.06±0.14mm in this new modality of 3D printing is comparable to those described in literature for other types of bioprinting.
Robotic assisted 3D bio-printing demonstrated here is a viable option for focal cartilage defect restoration.
We investigated the feasibility of Remote Centre of Motion (RCM) and viscous material extrusion 3D printing. A hypothetical, intra-articular, regenerative medicine-based treatment technique for focal cartilage defects of the knee was used as a potential example of the application of 3D printing in vivo.
The results of this study suggest, that RCM mechanism is feasible with viscous material extrusion 3D printing processes, without a major trade-off in imprint quality.
The achieved printing accuracy at an average dimensional error of 0.06±0.14mm in this new modality of 3D printing is comparable to those described in literature for other types of bioprinting.
Robotic assisted 3D bio-printing demonstrated here is a viable option for focal cartilage defect restoration.
Original language | English |
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Article number | 3746 |
Number of pages | 9 |
Journal | Scientific Reports |
Volume | 9 |
Issue number | 1 |
DOIs | |
Publication status | Published - 6 Mar 2019 |
Keywords
- 3D bioprinting
- cartilage defects
- focal cartilage
- Remote Centre of Motion (RCM)
- printing accuracy
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Profiles
Projects
- 1 Finished
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Medical Devices Doctoral Training Centre Renewal
EPSRC (Engineering and Physical Sciences Research Council)
1/10/08 → 31/03/18
Project: Research - Studentship
Datasets
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Remote centre of motion printing experiment data
Lipskas, J. (Creator), Yao, W. (Contributor) & Deep, K. (Contributor), University of Strathclyde, 8 Feb 2019
DOI: 10.15129/261432c4-ad25-47e4-a5fa-a3420e35a76c
Dataset