Revolutionizing prokaryotic systematics through next-generation sequencing

Vartul Sangal, Leena Nieminen, Nicholas P. Tucker, Paul A. Hoskisson

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Citations (Scopus)

Abstract

Next-generation sequencing has revolutionized modern research in all life sciences. It has been applied in studying evolution, global transmission and local adaptation of pathogens, microbial ecology, genetics and physiology. In this chapter, we have provided a brief summary of recent advances in sequencing technologies and easy to use bioinformatic tools to analyse sequence data, with a focus on prokaryotic biology. We have emphasized the importance of routinely applying whole genome sequencing in prokaryotic systematics, evolution, genotyping and functional characterization.

LanguageEnglish
Title of host publicationNew Approaches to Prokaryotic Systematics
EditorsMichael Goodfellow, Iain Sutcliffe, Jongsik Chun
Pages75-101
Number of pages27
DOIs
Publication statusPublished - 28 Aug 2014

Publication series

NameMethods in Microbiology
PublisherElsevier
Volume41

Fingerprint

Microbial Genetics
Biological Science Disciplines
Ecology
Computational Biology
Sequence Analysis
Genome
Technology
Research

Keywords

  • bioinformatic tools
  • comparative genomics
  • de novo assembly
  • genome annotation
  • mapping
  • next-generation sequencing
  • phylogenetic analyses
  • prokaryotic systematics

Cite this

Sangal, V., Nieminen, L., Tucker, N. P., & Hoskisson, P. A. (2014). Revolutionizing prokaryotic systematics through next-generation sequencing. In M. Goodfellow, I. Sutcliffe, & J. Chun (Eds.), New Approaches to Prokaryotic Systematics (pp. 75-101). (Methods in Microbiology; Vol. 41). https://doi.org/10.1016/bs.mim.2014.07.001
Sangal, Vartul ; Nieminen, Leena ; Tucker, Nicholas P. ; Hoskisson, Paul A. / Revolutionizing prokaryotic systematics through next-generation sequencing. New Approaches to Prokaryotic Systematics. editor / Michael Goodfellow ; Iain Sutcliffe ; Jongsik Chun. 2014. pp. 75-101 (Methods in Microbiology).
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Sangal, V, Nieminen, L, Tucker, NP & Hoskisson, PA 2014, Revolutionizing prokaryotic systematics through next-generation sequencing. in M Goodfellow, I Sutcliffe & J Chun (eds), New Approaches to Prokaryotic Systematics. Methods in Microbiology, vol. 41, pp. 75-101. https://doi.org/10.1016/bs.mim.2014.07.001

Revolutionizing prokaryotic systematics through next-generation sequencing. / Sangal, Vartul; Nieminen, Leena; Tucker, Nicholas P.; Hoskisson, Paul A.

New Approaches to Prokaryotic Systematics. ed. / Michael Goodfellow; Iain Sutcliffe; Jongsik Chun. 2014. p. 75-101 (Methods in Microbiology; Vol. 41).

Research output: Chapter in Book/Report/Conference proceedingChapter

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Sangal V, Nieminen L, Tucker NP, Hoskisson PA. Revolutionizing prokaryotic systematics through next-generation sequencing. In Goodfellow M, Sutcliffe I, Chun J, editors, New Approaches to Prokaryotic Systematics. 2014. p. 75-101. (Methods in Microbiology). https://doi.org/10.1016/bs.mim.2014.07.001