Resonance Raman scattering of catalytic beacons for DNA detection

Kristy S. McKeating; Duncan Graham; Karen Faulds

doi:10.1039/c3cc40346g

Resonance Raman scattering of catalytic beacons for DNA detection

Kristy S. McKeating
, Duncan Graham
, Karen Faulds

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.

Original language	English
Pages (from-to)	3206-3208
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	31
Early online date	14 Mar 2013
DOIs	https://doi.org/10.1039/c3cc40346g
Publication status	Published - 21 Apr 2013

Keywords

catalytic action
DNA detection
Raman scattering
colorimetric techniques

Access to Document

10.1039/c3cc40346g

Cite this

@article{c67cebad9d63432f86fcd1ef19cbbfa1,

title = "Resonance Raman scattering of catalytic beacons for DNA detection",

abstract = "A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.",

keywords = "catalytic action, DNA detection, Raman scattering, colorimetric techniques",

author = "McKeating, \{Kristy S.\} and Duncan Graham and Karen Faulds",

year = "2013",

month = apr,

day = "21",

doi = "10.1039/c3cc40346g",

language = "English",

volume = "49",

pages = "3206--3208",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "31",

}

TY - JOUR

T1 - Resonance Raman scattering of catalytic beacons for DNA detection

AU - McKeating, Kristy S.

AU - Graham, Duncan

AU - Faulds, Karen

PY - 2013/4/21

Y1 - 2013/4/21

N2 - A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.

AB - A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.

KW - catalytic action

KW - DNA detection

KW - Raman scattering

KW - colorimetric techniques

UR - https://www.scopus.com/pages/publications/84875463738

U2 - 10.1039/c3cc40346g

DO - 10.1039/c3cc40346g

M3 - Article

SN - 1359-7345

VL - 49

SP - 3206

EP - 3208

JO - Chemical Communications

JF - Chemical Communications

IS - 31

ER -

Resonance Raman scattering of catalytic beacons for DNA detection

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Wolfson Merit Award: Responsive Nanoparticles for Multi-Modal Imaging

Cite this

Resonance Raman scattering of catalytic beacons for DNA detection

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Projects

Wolfson Merit Award: Responsive Nanoparticles for Multi-Modal Imaging

Cite this