Resonance Raman scattering of catalytic beacons for DNA detection

Kristy S. McKeating, Duncan Graham, Karen Faulds

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.

LanguageEnglish
Pages3206-3208
Number of pages3
JournalChemical Communications
Volume49
Issue number31
Early online date14 Mar 2013
DOIs
Publication statusPublished - 21 Apr 2013

Fingerprint

Catalytic DNA
Peroxidase
Raman scattering
Assays
DNA
Oxidation
Substrates

Keywords

  • catalytic action
  • DNA detection
  • Raman scattering
  • colorimetric techniques

Cite this

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abstract = "A novel method for analysing the catalytic action of a DNAzyme is reported. Resonance Raman scattering (RRS) is shown to successfully monitor the oxidation of two different peroxidase substrates and has been implemented in an assay for the detection of target DNA, providing a more sensitive method of analysis than current colorimetric techniques.",
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Resonance Raman scattering of catalytic beacons for DNA detection. / McKeating, Kristy S.; Graham, Duncan; Faulds, Karen.

In: Chemical Communications, Vol. 49, No. 31, 21.04.2013, p. 3206-3208.

Research output: Contribution to journalArticle

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