Relationships between radiological and biochemical-evidence of rickets in asian schoolchildren

A.A. Abdul-Motaal, G. Gettinby, W B McIntosh, G R Sutherland, M G Dunnigan

Research output: Contribution to journalArticle

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Abstract

One hundred Asian schoolchildren provided evidence of the relationships between radiological and biochemical evidence of rickets in a vitamin D-deficient population. In a retrospective study of the X-rays of 56 children the variables serum alkaline phosphatase, inorganic phosphorus and age provided a discriminant function which correctly classified 10 of 11 children with radiological evidence of rickets and 44 of 45 children with negative or marginally abnormal X-rays. When the discriminant function was applied to a prospective study of 44 children, three children with radiological evidence of rickets were correctly classified together with 38 of the remaining 41 children with negative or marginally abnormal X-rays. Serum alkaline phosphatase was the most important variable in the discriminant analysis, followed by serum inorganic phosphorus and age. Low levels of serum 25-hydroxy vitamin D (25-OHD) are of little value in predicting the severity of radiological evidence of rachitic bone disease in a vitamin D-deficient population.
LanguageEnglish
Pages307-312
Number of pages5
JournalPostgraduate Medical Journal
Volume61
Issue number714
DOIs
Publication statusPublished - 1985

Fingerprint

Rickets
Vitamin D
X-Rays
Serum
Phosphorus
Alkaline Phosphatase
Bone Diseases
Discriminant Analysis
Population
Retrospective Studies
Prospective Studies

Keywords

  • radiological evidence
  • biochemical-evidence
  • rickets
  • asian schoolchildren
  • vitamin D-deficient

Cite this

Abdul-Motaal, A. A., Gettinby, G., McIntosh, W. B., Sutherland, G. R., & Dunnigan, M. G. (1985). Relationships between radiological and biochemical-evidence of rickets in asian schoolchildren. Postgraduate Medical Journal, 61(714), 307-312. https://doi.org/10.1136/pgmj.61.714.307
Abdul-Motaal, A.A. ; Gettinby, G. ; McIntosh, W B ; Sutherland, G R ; Dunnigan, M G. / Relationships between radiological and biochemical-evidence of rickets in asian schoolchildren. In: Postgraduate Medical Journal. 1985 ; Vol. 61, No. 714. pp. 307-312.
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Abdul-Motaal, AA, Gettinby, G, McIntosh, WB, Sutherland, GR & Dunnigan, MG 1985, 'Relationships between radiological and biochemical-evidence of rickets in asian schoolchildren' Postgraduate Medical Journal, vol. 61, no. 714, pp. 307-312. https://doi.org/10.1136/pgmj.61.714.307

Relationships between radiological and biochemical-evidence of rickets in asian schoolchildren. / Abdul-Motaal, A.A.; Gettinby, G.; McIntosh, W B; Sutherland, G R; Dunnigan, M G.

In: Postgraduate Medical Journal, Vol. 61, No. 714, 1985, p. 307-312.

Research output: Contribution to journalArticle

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