Relapse in Kala Azar: failure of sodium stibogluconate to clear parasites from organs other than the liver?

K. C. Carter, J. Alexander, A. J. Baillie, T. F. Dolan

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Relapse in Kala-azar is a common problem, occurring in 5–30% of patients (Chulay et al, 1983, Sanyal and Arora, 1979). Although this could be attributed to re-infection, there is a strong possibility that it may at least partly be due to treatment failure. Two recent studies suggest that removal of parasites from certain tissue sites may be difficult.
Original languageEnglish
Title of host publicationLeishmaniasis
Subtitle of host publicationthe current status and new strategies for control
EditorsD. T Hart
Place of PublicationBoston
PublisherSpringer Science + Business Media
Chapter5
Pages721-727
Number of pages7
Volume171
ISBN (Print)9781461288626
DOIs
Publication statusPublished - 1989

Keywords

  • visceral leishmaniasis
  • parasite burden
  • Muramyl Dipeptide
  • parasite number
  • sodium stibogluconate

Cite this

Carter, K. C., Alexander, J., Baillie, A. J., & Dolan, T. F. (1989). Relapse in Kala Azar: failure of sodium stibogluconate to clear parasites from organs other than the liver? In D. T. Hart (Ed.), Leishmaniasis: the current status and new strategies for control (Vol. 171, pp. 721-727). Springer Science + Business Media. https://doi.org/10.1007/978-1-4613-1575-9_89