Regiospecific synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles via photochemically generated nitrile imine intermediates

Sam Stewart, Robert Harris, Craig Jamieson

Research output: Contribution to journalArticle

9 Citations (Scopus)
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Abstract

The synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles was achieved under photochemical conditions. This simple and mild one-step reaction provides regiospecific access to 2,4,5-substituted 1,2,3-triazoles via a nitrile imine intermediate. Syntheses of alkyl and heterocylic derivatives were also investigated.
Original languageEnglish
Pages (from-to)2480-2484
Number of pages5
JournalSynlett
Volume25
Issue number17
Early online date8 Sep 2014
DOIs
Publication statusPublished - 2014

Keywords

  • photochemistry
  • regioselectivity
  • tetrazole
  • triazole
  • indazole

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