Recent advances in the generation of nitrilium betaine 1,3-dipoles

Keith Livingstone, Gemma Little, Craig Jamieson

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)
5 Downloads (Pure)


Nitrilium betaine 1,3-dipoles are ubiquitous reagents in organic chemistry, with applications ranging from natural product synthesis to materials science. Given the high reactivity of these zwitterionic motifs, they are invariably generated in situ from a suitable precursor, prior to use. This short review summarises the recent progress in the development of modern approaches towards the formation of these 1,3-dipoles, and their applications within a diverse range of fields.

Original languageEnglish
Pages (from-to)2399-2407
Number of pages9
Issue number14
Early online date11 Feb 2021
Publication statusPublished - 20 Jul 2021


  • 1,3-dipole
  • dipolar cycloaddition
  • nitrile imine
  • nitrile oxide
  • nitrile ylide
  • nitrilium betaine
  • photochemistry


Dive into the research topics of 'Recent advances in the generation of nitrilium betaine 1,3-dipoles'. Together they form a unique fingerprint.

Cite this