Real-time multimodal imaging of nanoparticle-cell interactions in high-throughput microfluidics

C.A. Cunha Matos, O.M. Millington, A. W. Wark, M. Zagnoni

Research output: Chapter in Book/Report/Conference proceedingConference contribution book

2 Citations (Scopus)

Abstract

We present an interdisciplinary approach that allows for the evaluation of nanoparticle cytotoxicity at the single-cell level. By combining single-cell microfluidics with nanoparticle chemistry, real-time and high-throughput multimodal imaging of cellular interactions with functionalised gold nanorods was
successfully achieved. The integration of such techniques into tools for high-resolution cell monitoring and drug screening has, to the best of our knowledge, not been reported.
Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014)
Place of PublicationSan Diego, CA.
Pages968-970
Number of pages3
Publication statusPublished - 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) - Texas, San Antonio, United States
Duration: 26 Oct 201430 Oct 2014

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014)
CountryUnited States
CitySan Antonio
Period26/10/1430/10/14

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Keywords

  • multimodal imaging
  • nanoparticles
  • cell interactions
  • single-cell
  • gold nanoparticles
  • nanotoxicity
  • high-throughput assay

Cite this

Cunha Matos, C. A., Millington, O. M., Wark, A. W., & Zagnoni, M. (2014). Real-time multimodal imaging of nanoparticle-cell interactions in high-throughput microfluidics. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014) (pp. 968-970). San Diego, CA..