Rapid genotyping of Shigella sonnei using multiplex high resolution melting

Waleed Mazi, Vartul Sangal, Amir Saeed, Gunnar Sandstom, François-Xavier Weill , Jun Yu

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Shigella sonnei, an emerging global cause of shigellosis, consists of four distinct lineages and the current pandemic involves several geographically associated, multidrug- resistant clones that belong to lineage III (1-3). A typing scheme based on high resolution melting (HRM) of six chromosomal single nucleotide polymorphisms (SNPs) has been described to identify all lineages/sub-lineages (4).
Original languageEnglish
Article numberJCM.00874-15
Pages (from-to)1-2
Number of pages2
JournalJournal of Clinical Microbiology
Volume53
Issue number7
Early online date29 Apr 2015
DOIs
Publication statusE-pub ahead of print - 29 Apr 2015

Keywords

  • high resolution melting
  • shgiella sonnei
  • melting temperature
  • single nucleotide polymorphisms

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